Synthesis and Fluorescence Properties of Donor-Acceptor-Substituted Novel Dipyrazolo[3,4-b:3′,4′-d]Pyridines (DPP)

Abstract

A rapid and efficient method for the synthesis of novel dipyrazolo[3,4-b:3',4'-d]pyridines (DPP) from pyrazolo[3,4-b]pyridine was successfully developed. The DPP derivative was further N-alkylated (6, 8) as well as N-linked with amino acids (13) and their photophysical properties were studied along with N-aryl DPP 4 and observed that the chromophores at C(4) position in the aryl ring changed the absorption and emission lambda(max).

Synthesis of tetrasubstituted pyrazoles containing pyridinyl substituents

“…The pyrazole nucleus is a frequently occurring motif in many pharmaceuticals [1–2] and biologically active compounds [3–4], agrochemicals [5], dyes [6], fluorescent materials [7–8] and ligands of complexing agents [9–11]. Multiaryl-substituted pyrazoles are of special interest, with some drug molecules such as the nonsteroidal anti-inflammatory agent Lonazolac [12] or the well-known COX-2 inhibitor Celecoxib [13] as prominent representatives.…”

An Efficient Synthesis and Fluorescent Properties of Pyrazole[3,4‐b]thieno[2,3‐e]pyridine Derivatives

“…Because pyrazolo[3,4‐ b ]pyridine skeleton is a D‐π‐A system, some research concerning the fluorescent properties of its derivatives has been also disclosed. We envisioned that the fusion of pyrazolo[3,4‐ b ]pyridine and dihydrothiophen‐3(2 H )‐one 1,1‐dioxide core may contribute to the development of novel fluorescent materials with potential application.…”