Synthesis and spectroscopic characterization of some transition metal complexes of a new hexadentate N2S2O2 Schiff base ligand

Synthesis, Characterization and Antibacterial Activityof Schiff Bases Derived from 4-Dimethylaminobenzaldehyde with Some Amino Acids and 4-Aminoantipyrine toward Cu (II), Ni (II), Co (II), Cd (II) and Mn (II) Ions

“…All chemicals and reagents utilised in this study were laboratory pure purchased from Aldrich or BDH which include4-dimethylaminobenzaldehyde, L-valine, L-tyrosine, L-glycine, L-asparagine, 4-aminoantipyrine, NaOH, C 2 H 5 OH, CH 3 3 and dimethyl sulfoxide (DMSO).…”

“…The amino acid Schiff bases were prepared according to the following procedure:-NaOH (10 mmol, 0.4g) is dissolved in methanol (30 cm 3 ) and the amino acids [L-valine, L-tyrosine, L-glycine, L-asparagine or 4-aminoantipyrine] (10 mmol) were added to it. The mixtures were stirred with a magnetic there at room temperature.…”

“…Schiff bases obtained from the salicylaldehydes are popular polydentate ligands coordinated in neutral forms. Recently, metal complexes of Schiff bases are gaining popularity because of their antibacterial, antifungal and antitumor activities [2][3]. El-ajaily et al (4) studied the antibacterial activities of the Schiff base derived from the salicylaldehyde and cysteine and its Mn (II), Co(II), Ni (II), Cu (II) and Cd (II) complexes on some pathogenic bacteria.…”

Physicochemical studies and biological activity of mixed ligand complexes involving bivalent transition metals with a novel Schiff base and glycine as a representative amino acid

“…This band is absent in the spectra of metal(II) complexes, indicating coordination through the deprotonated phenolic OH group [35]. Moreover, it was evidenced by the shift in position of νCO (aromatic carbon and phenolic oxygen) at 1319 cm -1 [36] to the lower frequency region in the spectra of complexes [37]. However, the strong band observed at 1675 cm -1 in the free ATS ligand due to azomehtine group vibration is shifted towards lower frequencies in the complexes by (28-37 cm -1 ), suggesting that azomethine group is involved in coordination [38,39].…”

Preparation, Characterization and Biological Evaluation of β-Lactam Derived from 6-Amino Penicillinic Acid and Salicyldehyde

“…Chelating ligands containing N, S and O donor atoms show broad biological activity and are of special interest because of the variety of ways in which they are bonded to metal ions. These ligands can be classified by the number of site that gives electrons to the ion metallic (single claw Bidentate, tridentate, Tetradentate, etc.,) [4][5][6][7][8][9], it is known that the existence of metal ion bonded to biologically active compounds may enhance their activities Schiff base ligands with nitrogen donor atoms of the azomethine group and anther donor atoms of the Schiff base ligand such as oxygen of carboxylic group afforded stable complexes with various transition metals. Beta-Lactam considered important item of antibiotics that contain a (C=O) group in β-Lactam ring in structural [10].…”