Synthesis and structure of antibacterial coatings formed by electron-beam dispersion of polyvinyl chloride in vacuum

He, Chun; Rogachev, A.V.; Li, Beibei; Yarmolenko, V.A.; Тапальский, Д. В.; Jiang, Xiaohong; Sun, Dongping; Yarmolenko, М.А.

doi:10.1016/j.surfcoat.2018.09.013

Cited by 5 publications

(1 citation statement)

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“…Staphylococcus aureus (S. aureus ATCC12600) and Escherichia coli (E. coli ATCC 25922) were used for the microbiological studies. The activity was assessed using a standard agar technique [18,19]. The coated titanium plates were previously cut into circles with a diameter of 6 mm.…”

Section: Methodsmentioning

confidence: 99%

Structures and Antibacterial Properties of PLA-based Ciprofloxacin Composite Films Deposited by Low-Electron Beam Dispersion

Jiang

et al. 2020

Eurasian Chem. Tech. J.

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Polylactic acid (PLA)-based ciprofloxacin (Cip) antibacterial films with mass ratio PLA:Cip=1:1 were prepared by low-electron beam dispersion (EBD). The molecular structure, chemical composition and morphology of PLA-based ciprofloxacin antibacterial films were investigated by XPS, FTIR, liquid NMR and SEM. The antibacterial activity of composite films was tested against E. coli ATCC 25922 and S. aureus ATCC 12600 using the agar diffusion method on the solid LB agar medium. XPS and FTIR analysis showed the presence of an antibacterial ingredient in the composite films. Using NMR, it has been shown that the molecular structure of a monolayer of ciprofloxacin is fully consistent with the molecular structure of the initial ciprofloxacin powder. High antibacterial activity of the composite films has been also established and the layers still possess antibacterial activity with regard to S. aureus even after 7 days of leaching in an isotonic solution. The thermal treatment indicates that the composite films can withstand temperatures of 180 °C and keep its structure unchanged.

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Section: Methodsmentioning

confidence: 99%