Synthesis, characterization and luminescence properties of Eu3+-doped hydroxyapatite nanocrystal and the thermal treatment effects

Silva, Flávia R. O.; Lima, Nelson Batista de; Bressiani, Ana Helena A.; Courrol, Lilia Coronato; Gomes, Laércio

doi:10.1016/j.optmat.2015.07.006

Cited by 38 publications

(22 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In particular, according to [52], our results show the most intense and sharp emission bands for the sample annealed at 900 °C. Photoluminescence of europium ions (Er 3+ ) have been widely used as spectral probe in the crystallographic investigation of activation centers [52,53]. Among all emission transitions, the 5 D0 7 F0 transition is significant in that it indicates the presence of multiple cationic sites present in the host nanocrystal structure.…”

Section: Luminescence Spectroscopysupporting

confidence: 62%

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

et al. 2020

View full text Add to dashboard Cite

Europium-doped hydroxyapatite Ca10(PO4)6(OH)2 (3% mol) powders were synthesized by an optimized chemical precipitation method at 25 °C, followed by drying at 120 °C and calcination at 450 °C and 900 °C. The obtained nanosized crystallite samples were investigated by means of a combination of inductively coupled plasma (ICP) spectroscopy, powder X-ray diffraction (PXRD), Fourier Transform Infrared (FTIR), Raman and photoluminescence (PL) spectroscopies. The Rietveld refinement in the hexagonal P63/m space group showed europium ordered at the Ca2 site at high temperature (900 °C), and at the Ca1 site for lower temperatures (120 °C and 450 °C). FTIR and Raman spectra showed slight band shifts and minor modifications of the (PO4) bands with increasing annealing temperature. PL spectra and decay curves revealed significant luminescence emission for the phase obtained at 900 °C and highlighted the migration of Eu from the Ca1 to Ca2 site as a result of increasing calcinating temperature.

show abstract

Section: Luminescence Spectroscopysupporting

confidence: 62%

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

et al. 2020

View full text Add to dashboard Cite

show abstract

“…Chemical modifications, for example, elemental substitutions, have been implemented to modulate tissue reactions to the implanted HAp material . In addition, a large number of researches showed that modification of HAp with various elements, such as Ce, Mg, Er, Sr, Si, Eu, and Zn, etc., leads to a significant reduction in the particle sizes and, thus, promotes formation of nanocrystalline HAp. Our interest is devoted to the modification of synthesis products with Mg and Sr, as it has been established that these ions have potential for application as a tool to improve the biological performance of various biomaterials including HAp .…”

Section: Introductionmentioning

confidence: 99%

Low‐temperature synthesis of nanocrystalline hydroxyapatite: Effect of Mg and Sr content

2017

View full text Add to dashboard Cite

Nanocrystalline Mg-or Sr-containing hydroxyapatite powders were synthesized through low-temperature chemical precipitation. The most significant factor for reduction in particle sizes included adjusting the reaction temperature between 0°C and 50°C. Syntheses products were characterized using several analytical tools to determine purity and influence of added amount (up to 15 mol%) of Mg or Sr on the composition and structure. Qualitative analysis by Fourier transform infrared spectroscopy and low intensity, broad X-ray diffraction peaks indicated the presence of nanocrystalline and/or amorphous hydroxyapatite in all the products. Moreover, a significant decrease in the crystallinity was observed with increasing Mg (up to 2.8 AE 0.3 wt%) and Sr (up to 9.6 AE 1.0 wt%) concentration. N 2 adsorption and scanning electron microscopy characterizations confirmed the nanocrystalline nature of the synthesized products. The synthesized products had nanosized spherical-like particle morphology with the specific surface area ranging from 89 AE 7 to 150 AE 20 m 2 /g. K E Y W O R D Sbiomaterials, crystal structure, hydroxyapatite, nucleation, precipitation

show abstract

“…Zhou and Bhaduri reported the use of Y 3+ doped HA in radiation therapy and biomedical applications. Among the lanthanides, Eu 3+ is a suitable activator for doping into apatite family since they exhibit stable luminescence, high thermal and chemical stabilities, sharp emission band, and good biocompatibility …”

Section: Introductionmentioning

confidence: 99%

“…Among the lanthanides, Eu 31 is a suitable activator for doping into apatite family since they exhibit stable luminescence, high thermal and chemical stabilities, sharp emission band, and good biocompatibility. [27][28][29] Furthermore, the inclusion of a mineral ion with bioactive property into HA nanoparticles might enhance the biological properties of the implants. 25 In particular, the beneficial effect of different bioactive ions such as Sr 21 , Ba 21 , Mg 21 , and Zn 21 for substitution into pure HA was reported by Gopi et al 30 Recent studies focus on the substitution with dual minerals in calcium apatite for many biological and medical applications.…”

Section: Introductionmentioning

confidence: 99%

In‐vitro biocompatibility, bioactivity and photoluminescence properties of Eu³⁺/Sr²⁺ dual‐doped nano‐hydroxyapatite for biomedical applications

et al. 2017

View full text Add to dashboard Cite

In the present investigation, we have successfully synthesized luminescent Eu -doped and Eu /Sr codoped hydroxyapatite (HA) nanoparticles through sol-gel assisted precipitation method with the aim of developing novel biomaterials containing osteoblast mineral (Sr ) and luminescence activator (Eu ). The structure, morphology, thermal stability, and luminescence properties of the resultant spherical nanoparticles (50-100 nm diameters) were studied. Moreover, the in-vitro bioactivity of Eu Sr HA nanoparticles was investigated by immersing in the simulated body fluid for many weeks. The antimicrobial activity results against gram positive and gram negative bacterial stains, showed better resistivity for the Eu Sr HA among the other compositions. The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay of live/dead cells cultured with Eu /Sr -doped HA nanoparticles retained its normal morphology and did not show a significant impact on cell proliferation at various incubation days, which evidence for the material's superior biocompatible nature even at a higher concentration of 375 µg/mL. Thus, the incorporation of dual ions in HA nanoparticles with strong luminescence properties develops potential biomaterial for live cell imaging and in nanomedicine. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2191-2201, 2018.

show abstract

Synthesis, characterization and luminescence properties of Eu3+-doped hydroxyapatite nanocrystal and the thermal treatment effects

Cited by 38 publications

References 31 publications

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

Low‐temperature synthesis of nanocrystalline hydroxyapatite: Effect of Mg and Sr content

In‐vitro biocompatibility, bioactivity and photoluminescence properties of Eu³⁺/Sr²⁺ dual‐doped nano‐hydroxyapatite for biomedical applications

Contact Info

Product

Resources

About

Synthesis, characterization and luminescence properties of Eu3+-doped hydroxyapatite nanocrystal and the thermal treatment effects

Cited by 38 publications

References 31 publications

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

Crystal Chemistry and Luminescence Properties of Eu-Doped Polycrystalline Hydroxyapatite Synthesized by Chemical Precipitation at Room Temperature

Low‐temperature synthesis of nanocrystalline hydroxyapatite: Effect of Mg and Sr content

In‐vitro biocompatibility, bioactivity and photoluminescence properties of Eu3+/Sr2+ dual‐doped nano‐hydroxyapatite for biomedical applications

Contact Info

Product

Resources

About

In‐vitro biocompatibility, bioactivity and photoluminescence properties of Eu³⁺/Sr²⁺ dual‐doped nano‐hydroxyapatite for biomedical applications