Synthesis, characterization, and photochemical properties of novel peripherally and non-peripherally tetra substituted zinc(II) and magnesium(II) phthalocyanines containing 4-(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)phenol units

Peripherally, non-peripherally and axially pyrazoline-fused phthalocyanines: synthesis, aggregation behaviour, fluorescence, singlet oxygen generation, and photodegradation studies

“…42 The singlet oxygen quantum yields (F D ) of the synthesized HY-ZnPc p , HY-ZnPc np , and HY-SiPc were determined by a chemical method using 1,3diphenylisobenzofuran (DPBF) as a singlet oxygen quencher in DMSO (not a toxic solvent). 37,44 The spectral changes during the determination of F D for pyrazoline-fused peripheral and non-peripheral zinc phthalocyanines (HY-ZnPc p and HY-ZnPc np ) in DMSO are given in Fig. 8.…”

“…[30][31][32][33][34][35][36] No studies on the photochemical properties of pyrazoline substituted phthalocyanine compounds were found in the literature. 37 In this study, we aimed to examine the contribution of the pyrazoline compound containing the methoxy group to the photophysical and photochemical properties, unlike the pyrazoline compound in the other study. In addition, unlike the other study, we examined the contribution of silicon phthalocyanine compound containing methoxylated pyrazoline group to photophysical and photochemical properties.…”

Nanoparticle-Based Drug Delivery Systems for Photodynamic Therapy of Metastatic Melanoma: A Review

“…In addition, they demonstrate negligible side effects, which is attributed to increased tumor selectivity and rapid elimination of the PS from the body [23]. Among the second-generation PSs, phthalocyanines (Pcs) are widely used PSs containing a central diamagnetic metal ion (e.g., zinc, aluminum, or magnesium) that significantly increases the triplet-state quantum yield of ROS generation and photostability, as well as achieving deeper tissue penetration with minimal side effects [32]. Studies by Valli and colleagues [33] noted that photoactivated zinc phthalocyanine (ZnPcS) demonstrated an increased level of ROS generation, which triggered apoptosis and necrosis in MM cells [33].…”

Quinoline‐fused both non‐peripheral and peripheral ZnIIand MgIIphthalocyanines: Anti‐cholinesterase, anti‐α‐glucosidase, DNA nuclease, antioxidant activities, and in silico studies

“…It has been reported in studies that researchers examined that phthalocyanine derivatives containing substituted groups such as aryloxy, alkoxy, alkyl, alkylthio chains, and bulky groups have better solubility. [ 24 ]…”

“…It has been reported in studies that researchers examined that phthalocyanine derivatives containing substituted groups such as aryloxy, alkoxy, alkyl, alkylthio chains, and bulky groups have better solubility. [24] Substituents attached to the phthalocyanine core are the most important factors affecting their use in many modern application areas. In this study, we wanted to examine the biological activity properties of quinolinefused phthalocyanine compounds.…”