Synthesis of efficient bacterial adhesion-resistant coatings by one-step polydopamine-assisted deposition of branched polyethylenimine-g-poly(sulfobetaine methacrylate) copolymers

Ran, Bin; Jing, Chengyu; Yang, Chen; Li, Xiaonan; Li, Yihe

doi:10.1016/j.apsusc.2018.04.184

Cited by 20 publications

(13 citation statements)

References 45 publications

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“…Both bacteria S. aureus and E. coli have a negative charge on the outer surface due to phospholipids in the structure and repelled by the copolymers containing anionic SO 3 groups in SPMA monomer due to repulsive electrostatic interactions [53]. These results suggested that higher concentrations of SPMA monomer in the copolymer compositions may have produced more repulsion between polymer and bacteria [35,54]. This increase in SPMA monomer concentration in copolymers resulted in enhanced water hydrogen bonding and lower fouling [21].…”

Section: Contact Angle and Surface Energymentioning

confidence: 95%

“…Drying was carried out in sterile petri plates to avoid contamination. After drying, samples were placed at -4°C until subjected to SEM analysis [35]. Dictyosphaerium microalgae were employed for biofilm formation testing.…”

Section: Characterization and Bioassaymentioning

confidence: 99%

“…This increase in SPMA monomer concentration in copolymers resulted in enhanced water hydrogen bonding and lower fouling [21]. These anionic copolymers are capable of effectively interacting with water molecules that resulted in lower settlement of bacteria to higher extent [35].…”

Section: Contact Angle and Surface Energymentioning

confidence: 99%

“…SEM images have also shown low adhesion of E. coli and S. aureus on the surface due to the hydrophilic and anionic nature of SPMA monomer [49,51]. The bacteria motility is expected to diminish on negatively charged polymers and resulted in protein denaturation, enzyme denaturation, and microbial death by rupturing the cell wall of Gram-negative bacteria E. coli and Gram-positive bacteria S. aureus [35,53,60]. In Figures 8 and 9, adhesion of E. coli and S. aureus on the surface of 3.7.…”

Section: Advances In Polymer Technologymentioning

confidence: 99%

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Transpicuous-Cum-Fouling Resistant Copolymers of 3-Sulfopropyl Methacrylate and Methyl Methacrylate for Optronics Applications in Aquatic Medium and Healthcare

Mushtaq

Ahmad

Nasir

et al. 2020

Advances in Polymer Technology

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The scope of optical sensors and scanners in aquatic media, fluids, and medical diagnostics has been limited by paucity of transparent shielding materials with antifouling potential. In this research endeavor, facile synthesis, characterization, and bioassay of antifouling transparent functional copolymers are reported. Copolymers of 3-sulfopropyl methacrylate (SPMA) and methyl methacrylate (MMA) were synthesized by free radical polymerization in various proportions. Samples PSM20, PSM30, PSM40, PSM50, and PSM60 contain 20%, 30%, 40%, 50%, and 60% SPMA by weight, respectively. Resultant products were characterized by FTIR and 1H-NMR spectroscopy. The synthesized copolymers have exhibited excellent transparency, i.e., 75% to 88%, as determined by the UV-Vis spectroscopic analysis. Transmittance was decreased from 6% to 2% in these copolymers upon changing the concentration of 3-sulfopropyl methacrylate from 20% to 50% owing to bacterial and algal biofilm formation. Water contact angle values were ranged from 18° to 63° and decreased with the increase in the polarity of copolymers. The surface energy lowest value 58 mJ/m2 and highest value 72 mJ/m2 were calculated for PSM20 and PSM50, respectively, by the Chibowski approach and Young equation. Sample PSM50 has exhibited the highest antibacterial activities, i.e., 18 mm and 19 mm, against Escherichia coli and Staphylococcus aureus, respectively, by the disk diffusion method. Copolymer PSM50 has shown minimum algal adhesion for Dictyosphaerium algae as observed by optical microscopy. This lower bacterial and algal adhesion is attributed to higher concentrations of anionic SPMA monomer that cause electrostatic repulsion between functional groups of the polymer and microorganisms. Thus, the resultant PSM50 product has exhibited good potential for optronics shielding application in aquatic medium and medical diagnostics.

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Section: Contact Angle and Surface Energymentioning

confidence: 95%

Section: Characterization and Bioassaymentioning

confidence: 99%

Section: Contact Angle and Surface Energymentioning

confidence: 99%

Section: Advances In Polymer Technologymentioning

confidence: 99%

See 2 more Smart Citations

Transpicuous-Cum-Fouling Resistant Copolymers of 3-Sulfopropyl Methacrylate and Methyl Methacrylate for Optronics Applications in Aquatic Medium and Healthcare

Mushtaq

Ahmad

Nasir

et al. 2020

Advances in Polymer Technology

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“…In the case of polybetaines the chemical method is often used to obtain the polybetaine polymer-based surface coatings (surface brushes and adhering membrane) [55,68,69]. There are a variety of polymer coating methods as follows: drop-casting coating method [70], cast-coating [71], tape casting [72], spraying method [73] and spin coating technologies [74].…”

mentioning

confidence: 99%

Polybetaines in Biomedical Applications

Racoviţă¹,

Trofin²,

Loghin³

et al. 2021

IJMS

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Polybetaines, that have moieties bearing both cationic (quaternary ammonium group) and anionic groups (carboxylate, sulfonate, phosphate/phosphinate/phosphonate groups) situated in the same structural unit represent an important class of smart polymers with unique and specific properties, belonging to the family of zwitterionic materials. According to the anionic groups, polybetaines can be divided into three major classes: poly(carboxybetaines), poly(sulfobetaines) and poly(phosphobetaines). The structural diversity of polybetaines and their special properties such as, antifouling, antimicrobial, strong hydration properties and good biocompatibility lead to their use in nanotechnology, biological and medical fields, water remediation, hydrometallurgy and the oil industry. In this review we aimed to highlight the recent developments achieved in the field of biomedical applications of polybetaines such as: antifouling, antimicrobial and implant coatings, wound healing and drug delivery systems.

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Novel Antimicrobial Coating on Silicone Contact Lens Using Glycidyl Methacrylate and Polyethyleneimine Based Polymers

Pillai

Reghu

Vikhe

et al. 2020

Macromol. Rapid Commun.

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Contact lenses are medical devices commonly used to correct refractive errors and to maintain ocular health. Microorganisms such as bacteria that grow on the lens surface cause irritation to the eyes and can even cause loss of vision. In this paper, two different coating strategies are employed to form an efficient antimicrobial coating on contact lenses. In the first method, a presynthesized copolymer of polyethyleneimine‐graft‐polyethylene glycol methacrylate (PEI‐PEGMA) is used and the coated lenses show antimicrobial activity (in vitro) against methicillin‐resistant Staphylococcus aureus (MRSA) bacteria with killing efficacy >99.99% and log reduction of 5.1 and proxy host cell viability of 79%. In the second method, commercially available monomers/polymers such as glycidyl methacrylate (GMA), sulfobetaine methacrylate, and polyethyleneimine are used. A typical formulation consisting of 1% GMA shows antibacterial activity against MRSA with killing efficacy >99.99% and log reduction of 6.3. Proxy host cell viability for the coated lenses is found to be 90% indicating that the coating is nontoxic. Antibacterial coating reported here is very effective in killing gram‐positive bacteria such as MRSA and S. aureus. The second method using commercially available monomers/polymers involving a simple coating procedure is also easily scalable.

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Synthesis of efficient bacterial adhesion-resistant coatings by one-step polydopamine-assisted deposition of branched polyethylenimine-g-poly(sulfobetaine methacrylate) copolymers

Cited by 20 publications

References 45 publications

Transpicuous-Cum-Fouling Resistant Copolymers of 3-Sulfopropyl Methacrylate and Methyl Methacrylate for Optronics Applications in Aquatic Medium and Healthcare

Transpicuous-Cum-Fouling Resistant Copolymers of 3-Sulfopropyl Methacrylate and Methyl Methacrylate for Optronics Applications in Aquatic Medium and Healthcare

Polybetaines in Biomedical Applications

Novel Antimicrobial Coating on Silicone Contact Lens Using Glycidyl Methacrylate and Polyethyleneimine Based Polymers

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