Synthesis of Functionalized Coumarino[4,3-d]pyrazolo[3,4-b]pyridine Derivatives and Their Selective Recognition for Zn²⁺

Abstract

Ag ＋ 、Cr 3＋ 、Co 2＋ 、Cu 2＋ 、Pb 2＋ 、Sn 4＋ 、Fe 3＋ 、Zn 2＋ 等金属离子的作用, 结果表明化合物 3a 和 3b 对 Zn 2＋ 具有很好的选 择性识别能力.

Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction

“…Therefore, development and introduction of a convenient, efficient method for the synthesis of coumarin-fused pyrazolo[3,4- b ]pyridine is highly desirable for their immense pharmacological potential. As a part of our research on the synthesis of novel functionalized heterocyclic derivatives [40,41,42,43,44,45,46], in the current paper, we report a novel three-component domino reaction for the synthesis of functionalized coumarin-fused pyrazolo[3,4- b ]pyridine derivatives using silica sulfuric acid as the catalyst. It worth mentioning that participation of alcohols in construction of coumarin derivatives is described for the first time.…”