Synthesis of multirecognition magnetic molecularly imprinted polymer by atom transfer radical polymerization and its application in magnetic solid-phase extraction

Abstract

In this work, we reported an effective method for the synthesis of a multirecognition magnetic molecularly imprinted polymer (MMIP) with atom transfer radical polymerization (ATRP), using 2,4-diamino-6-methyl-1,3,5-triazine as pseudo-template. The resulting MMIP was characterized in detail by Fourier transform-infrared (FT-IR) spectra, scanning electron microscopy (SEM), thermogravimetic analysis (TGA), and vibrating sample magnetometry (VSM). These results indicated the successful synthesis of MMIP with sufficient thermal stability and magnetic properties. The adsorption experiments were carried out to evaluate the specific selectivity of MMIP related to the spatial structure of target molecules. The MMIP exhibited multirecognition ability and excellent binding capability for melamine (MEL), cyromazine (CYR), triamterene (TAT), diaveridine (DVD), and trimethoprim (TME), and the apparent maximum number of binding sites (Q ) was 77.5, 75.2, 72.5, 69.9, and 70.4 μmol g, respectively. The multirecognition MMIP not only possessed adequate magnetic responsiveness for fast separation but also avoided the risk of template leakage on trace component analysis. Therefore, it was suitable for serving as a magnetic solid-phase extraction (MSPE) adsorbent. MSPE coupled with high-performance liquid chromatography analysis was applied to enrich and separate five target molecules from three samples. Recoveries for all target molecules ranged from 81.6 to 91.5% with relative standard deviations of no more than 4.1% (n = 3). Graphical abstract Multirecognition property of magnetic molecularly imprinted polymer prepared with pseudo template.

Recent insights in magnetic hyperthermia: From the “hot-spot” effect for local delivery to combined magneto-photo-thermia using magneto-plasmonic hybrids

“…MIPs are prepared in presence of a template that serves as a mold for the formation of template complementary binding sites. The resulting molecularly imprinted polymers are being used in a wide range of applications, such as chiral separation [58,59], chemical sensing [60,61], competitive drug assays [62], chemical catalysis [63], or solid phase extraction [64,65]. MIP synthesis is reproducible, fast and economic.…”

Research Progress on Triarylmethyl Radical-Based High-Efficiency OLED

“…Due to their unique unpaired electron structure [ 16 ], stable organic radicals possess fascinating optical, electronic, and magnetic properties. Additionally, as a result, they have been widely used in the fields of polarization optics [ 17 , 18 , 19 , 20 ], organic optoelectronics [ 21 , 22 , 23 , 24 ], spintronics [ 25 , 26 , 27 , 28 ], and molecular magnetism [ 29 , 30 , 31 , 32 ]. However, in most cases, organic radicals have difficulty remaining stable under ambient conditions.…”

Synthesis of core‐shell magnetic molecularly imprinted polymer for the selective determination of imidacloprid in apple samples

“…The superior properties of MIPs include their high selectivity and sensitivity, low cost, physicochemical stability and reusability, which make them highly attractive materials . Currently, magnetic molecularly imprinted polymers (MMIPs) are attracting attention due to their versatility , specific and rapid magnetic separation ability , which allows the use of an external magnet to avoid centrifugation and filtration , good dispersion properties , high selectivity and sensitivity, and reusability . MMIPs have already been reported for imidacloprid detection ; however, the selectivity and sensitivity of MMIPs can be improved with different modification methods to achieve good results in complex matrix samples.…”