Synthesis of novel 1,2,3-triazole-containing pyridine–pyrazole amide derivatives based on one-pot click reaction and their evaluation for potent nematicidal activity against Meloidogyne incognita

Chen, Xiulei; Xiao, Youxin; Wang, Gaolei; Zhong, Li; Xu, Xiaoyong

doi:10.1007/s11164-015-2381-y

Cited by 9 publications

(4 citation statements)

References 25 publications

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“…This reveals that different substitution positions of the pyrazole ring may affect the mode of action of the compound and AChE inhibitions. In addition, the nematicidal activities of some representative aryl formamide compounds are shown in Table . − …”

Section: Chemical Nematicidal Active Compoundsmentioning

confidence: 99%

Chemical Nematicides: Recent Research Progress and Outlook

Chen

Song

2020

J. Agric. Food Chem.

129

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Plant-parasitic nematodes have caused huge economic losses to agriculture worldwide and seriously threaten the sustainable development of modern agriculture. Chemical nematicides are still the most effective means to manage nematodes. However, the long-term use of organophosphorus and carbamate nematicides has led to a lack of field control efficacy and increased nematode resistance. To meet the huge market demand and slow the growth of resistance, new nematicides are needed to enter the market. The rational design and synthesis of new chemical scaffolds to screen for new nematicides is still a difficult task. We reviewed the latest research progress of nematicidal compounds in the past decade, discussed the structure−activity relationship and mechanism of action, and recommended some nematicidal active fragments. It is hoped that this review can update the recent progress on nematicide discoveries and provide new ideas for the design and mechanism of action studies of nematicides.

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Section: Chemical Nematicidal Active Compoundsmentioning

confidence: 99%

Chemical Nematicides: Recent Research Progress and Outlook

Chen

Song

2020

J. Agric. Food Chem.

129

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“…However, the skeleton structure changes of them are mainly the replacement and modification of the pyrazole amide acid parent nucleus and aromatic amine, which is prone to cross-resistance. 18–23 Therefore, through introducing a new skeleton, there is room for pyrazole amide derivatives to further improve their biological activities.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1,2,4-oxadiazole

Shao

Yang

et al. 2022

RSC Adv.

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“…), which is expressed in a very low half minimal inhibitory concentration IC 50 values (≈2 nM) in some cases. Besides, compounds containing triazole moieties exhibited fungicidal (Tan et al, 2018) and antituberculous activities (Keri et al, 2015) as well as nematicide properties (Chen et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Supramolecular Systems Based on Novel Amphiphiles and a Polymer: Aggregation and Selective Solubilization

Gabdrakhmanov

Samarkina

Krylova

et al. 2019

J Surfact & Detergents

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Supramolecular systems based on novel triazole‐containing and pyrimidine‐containing amphiphiles bearing OH‐groups and a hydrophilic polymer (polyethyleneimine, PEI) were fabricated. Aggregation threshold of individual amphiphile solutions and a surfactant/polymer binary mixture were determined to be equal to 2 and 0.05 mM, respectively, using tensiometry and conductometry techniques. It was found, that PEI addition to surfactant aqueous solutions induces the transition from open to closed association mode accompanying the decrease of mean hydrodynamic diameter of particles (D H) from 100 nm to D H ≤ 5 nm. Polymer addition to the system results in the leveling of pH decrease with surfactant concentration and increase of the electrokinetic potential values from 10 mV up to 40 mV. It was established that solubilization capacity of the supramolecular system formed could be increased by transition from surfactant individual solutions to the amphiphile/polymer binary system. The solubilization properties of the system strongly depend on the nature of the hydrophobic guest solubilized and differ by two orders of magnitude for hydrophobic azodye and lipophilic oxime.

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Synthesis of novel 1,2,3-triazole-containing pyridine–pyrazole amide derivatives based on one-pot click reaction and their evaluation for potent nematicidal activity against Meloidogyne incognita

Cited by 9 publications

References 25 publications

Chemical Nematicides: Recent Research Progress and Outlook

Chemical Nematicides: Recent Research Progress and Outlook

Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1,2,4-oxadiazole

Supramolecular Systems Based on Novel Amphiphiles and a Polymer: Aggregation and Selective Solubilization

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