Synthesis of Novel Oligodeoxynucleotide Conjugates Containing the Anionophoric Moiety of Pamamycin

Uhlmann, Eugen; Hornung, L.; Will, David W.; Gräfe, U.

doi:10.1080/07328319808005179

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“…1,7-Diol-type solid supports 152 bearing the anionophoric product of alkaline hydrolysis of pamamycin, an antibiotic from Streptomyces aurantiacus with penetration enhancement potency, was used in the synthesis of a series of antisense oligodeoxynucleotides (Uhlmann et al, 1998).…”

Section: 141mentioning

confidence: 99%

Solid‐Phase Supports for Oligonucleotide Synthesis

Guzaev¹

2013

CP Nucleic Acid Chemistry

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This unit attempts to provide a reasonably complete inventory of over 280 solid supports available to oligonucleotide chemists for preparation of natural and 3'-modified oligonucleotides. Emphasis is placed on non-nucleosidic solid supports. The relationship between the structural features of linkers and their behavior in oligonucleotide synthesis and deprotection is discussed wherever the relevant observations are available.

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Section: 141mentioning

confidence: 99%