2015
DOI: 10.1016/j.jphotobiol.2015.03.033
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Synthesis, spectral, thermal, fluorescence, antimicrobial, anthelmintic and DNA cleavage studies of mononuclear metal chelates of bi-dentate 2H-chromene-2-one Schiff base

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Cited by 25 publications
(9 citation statements)
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“…Schiff bases are useful ligands and important organic fragments. The azomethine (C=N) functional group is a versatile pharmacophore for the design of bioactive compounds with a broad range of effects, including anti-inflammatory, 1,2) antibacterial, 3,4) antifungal, 3) analgesic, 2,5) antimicrobial, 3,6,7) anticonvulsant, 5) antitubercular, anticancer, 5,8) antioxidant, 9) anthelmintic, 10) antiglycation 11) and antidepressant. 12) Schiff bases are extensively employed as chelating ligands in the field of coordination chemistry.…”
mentioning
confidence: 99%
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“…Schiff bases are useful ligands and important organic fragments. The azomethine (C=N) functional group is a versatile pharmacophore for the design of bioactive compounds with a broad range of effects, including anti-inflammatory, 1,2) antibacterial, 3,4) antifungal, 3) analgesic, 2,5) antimicrobial, 3,6,7) anticonvulsant, 5) antitubercular, anticancer, 5,8) antioxidant, 9) anthelmintic, 10) antiglycation 11) and antidepressant. 12) Schiff bases are extensively employed as chelating ligands in the field of coordination chemistry.…”
mentioning
confidence: 99%
“…Among Schiff bases, the organotin(IV) complexes containing Nitrogen Sulfur (NS), Nitrogen Oxygen (NO), Oxygen Nitrgen Oxygen (ONO) and Oxygen Nitrogen Sulfur (ONS) donor atoms have shown great appeal due to their structural features, which can provide antimicrobial, antifungal, antibacterial, antioxidant and carcinostatic activity. 9,[13][14][15][16] The amino acids and their derivatives have been the subject of intense research efforts because of their coordination properties and potential for generating effective and less toxic metalbased drugs. Additionally, their physico-chemical properties and specific mechanism of transport facilitate facile biological uptake.…”
mentioning
confidence: 99%
“…Designing small molecules help in targeting specific sites on a DNA strand and can lead to novel therapeutic agents. Photocleavage study of DNA also helps in various applications like photodynamic therapy of cancers, DNA foot printing agents and in genomic research [42,43].…”
Section: Dna Cleavage Studiesmentioning
confidence: 99%
“…This also suggests that the unpaired electron exists in d x , i.e., G = 3.28 < 4.0. Here, g 11 < 2.3 explains the covalent nature of the M→L bonding [35]. The covalency parameter α 2 (= 0.44) is also calculated by using the following expression, which also suggests the covalent nature of the copper complexes.…”
Section: Esr Spectramentioning
confidence: 99%