Synthesis, stereochemistry and in vitro antimicrobial evaluation of novel 2-[(2,4-diaryl-3-azabicyclo[3.3.1]nonan-9-ylidene)hydrazono]-4-phenyl-2,3-dihydrothiazoles

Ramachandran, Rajamanickam; Parthiban, P.; Rani, M.; Jayanthi, Sampathkumar; Kabilan, S.; Jeong, Yeon Tae

doi:10.1016/j.bmcl.2011.08.115

Cited by 6 publications

(1 citation statement)

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“…Jeong and coworkers reported 2‐[(2,4‐diaryl‐3‐azabicyclo[3.3.1]nonan‐9‐ylidene)hydrazono]‐4‐phenyl‐2,3‐dihydrothiazoles by cyclizing 2‐[(2,4‐diaryl‐3‐azabicyclo[3.3.1]nonan‐9‐one thiosemicarbazones with phenacyl bromide. In comparison with Streptomycin and Amphotericin B, compounds were inspected against St. aureus , B. subtilis , S. typhi , E. coli , K. pneumoniae , C. neoformans , C. albicans , Rhizopus sp., A. niger and A. flavus for antimicrobial activity.…”

Section: Introductionmentioning

confidence: 99%

A retrospect on antimicrobial potential of thiazole scaffold

Mishra

Mujwar

et al. 2020

Journal of Heterocyclic Chem

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Due to its appreciable diversity in biological actions, thiazole and its substituted components, a significant class of heterocyclic compounds has developed as an influential scaffold in the field of chemical sciences. The variability of thiazole core has been expressed through the effective instigation of its anticancer (Dasatinib, Tiazofurin), antiretroviral (Ritonavir, Brecanavir), antimicrobial (Sulfathiazole, Ravuconazole) and anti-inflammatory (Fenclozic acid, Meloxicam) derivatives. This reasonable diversity in the physiological reaction pattern led many scientists to refine and develop new structural alternatives with much more efficient pharmacological action. This review is crucial for previous studies and projects to survey the antimicrobial activity of thiazole and thiazole related compounds to the mid of 2019.

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Section: Introductionmentioning

confidence: 99%