Synthesis, structural investigations and antimicrobial studies of hydrazone based ternary complexes with Cr(III), Fe(III) and La(III) ions

One Pot Synthesis of Cu(II) and Ni(II) Peroxo Complexes Containing Schiff Base: Physicochemical, Spectral and Antibacterial Investigations

“…To determine the susceptibility of the pathogenic microorganism to the synthesized compounds antibacterial screening was carried out. Among different methods the disc diffusion method is broadly admissible for performing the antibacterial screening of compounds [21][22][23][24][25]. The measured diameter of zone of inhibition for the activity of complexes are tabulated in Table 1.…”

Synthesis, Antibacterial Activity, and Molecular Docking Study of Bispyrazole‐Based Derivatives as Potential Antibacterial Agents

“…[1] Medicinal chemists are discovering chemical compounds that can be used as lead compounds in the field of Medicinal chemistry and drug discovery. Heterocyclic-based compounds play an important role in leading to the discovery of potent antibacterial agents.. [2][3][4][5][6][7][8] Heterocycles have sized large space in the field of organic chemistry and are a part of important biochemical processes inside the human body. Heterocycles are considered to be a skeleton of widely compounds in nature with different applications such as hormones, vitamins, alkaloids, pharmaceuticals, dyes, and agrochemicals.…”

“…Heterocyclic‐based compounds play an important role in leading to the discovery of potent antibacterial agents. [2–8] . Heterocycles have sized large space in the field of organic chemistry and are a part of important biochemical processes inside the human body.…”

Theoretical and Experimental Investigations of N‐ and O‐Alkylated Sulfonamides: Density Functional Theory, Hirshfeld Surface Analysis, and Molecular Docking Studies

“…It urged us to synthesize various N‐ and O ‐alkylated sulfonamides from the tranexamic acid derivatives of sulfonamide to improve biological applications and have quite lesser toxic effects. Due to significant structural properties and pharmacological applications of sulfonamides and their derivatives, we wish to report the synthesis and computational studies (FMOs, Global Reactivity Descriptors and Mulliken's Atomic Charges Analysis) of a new class of sulfonamides; 4‐{[Ethyl‐(naphthalene‐2‐sulfonyl)‐amino]‐methyl}‐cyclohexanecarboxylic acid ethyl ester ( IV ), 4‐[(2‐nitrobenzene‐1‐sulfonylamino)‐methyl]‐cyclohexanecarboxylic acid ethyl ester ( V ) and 4‐[(Cyclohexa‐1,5‐dienesulfonylamino)‐methyl]‐cyclohexanecarboxylic acid methyl ester ( VI ) [22–29] . The biological screening of these newly synthesized compounds was done to check their anti‐bacterial, anti‐fungal, anti‐oxidant, and enzyme inhibition potentials.…”

“…Due to significant structural properties and pharmacological applications of sulfonamides and their derivatives, we wish to report the synthesis and computational studies (FMOs, Global Reactivity Descriptors and Mulliken's Atomic Charges Analysis) of a new class of sulfonamides; 4-{[Ethyl-(naphthalene-2-sulfonyl)amino]-methyl}-cyclohexanecarboxylic acid ethyl ester (IV), 4-[(2-nitrobenzene-1-sulfonylamino)-methyl]-cyclohexanecarboxylic acid ethyl ester (V) and 4-[(Cyclohexa-1,5-dienesulfonylamino)-methyl]-cyclohexanecarboxylic acid methyl ester (VI). [22][23][24][25][26][27][28][29] The biological screening of these newly synthesized compounds was done to check their anti-bacterial, anti-fungal, antioxidant, and enzyme inhibition potentials. Molecular docking was also carried out to check their binding affinities with enzymes.…”