Synthesis, transfer, and characterization of core-shell gold-coated magnetic nanoparticles

Smith, McKenzie; McKeague, Maureen; DeRosa, Maria C.

doi:10.1016/j.mex.2019.02.006

Cited by 39 publications

(37 citation statements)

References 41 publications

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“…AuNPs have good potential for various applications, due to their properties such as Surface Plasmon Resonance and high biocompatibility. Adding ferromagnetism as an additional property to these nanoparticles enhances their applicability and use cases in medical treatment [78,79], for Magnetic Resonance Imaging [80], cancer treatment [81], drug delivery systems, as well as for catalysis, sensors, and so on [82][83][84][85]. Some initial experiments for determining the capability of producing such particles with USP were conducted, in order to investigate the formation mechanisms of these particles [86,87].…”

Section: Au/fe 2 O 3 Nanoparticlesmentioning

confidence: 99%

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Advances in Ultrasonic Spray Pyrolysis Processing of Noble Metal Nanoparticles—Review

Majerič

Rudolf

2020

Materials

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In the field of synthesis and processing of noble metal nanoparticles, the study of the bottom-up method, called Ultrasonic Spray Pyrolysis (USP), is becoming increasingly important. This review analyses briefly the features of USP, to underline the physical, chemical and technological characteristics for producing nanoparticles and nanoparticle composites with Au and Ag. The main aim is to understand USP parameters, which are responsible for nanoparticle formation. There are two nanoparticle formation mechanisms in USP: Droplet-To-Particle (DTP) and Gas-To-Particle (GTP). This review shows how the USP process is able to produce Au, Ag/TiO2, Au/TiO2, Au/Fe2O3 and Ag/(Y0.95 Eu0.05)2O3 nanoparticles, and presents the mechanisms of formation for a particular type of nanoparticle. Namely, the presented Au and Ag nanoparticles are intended for use in nanomedicine, sensing applications, electrochemical devices and catalysis, in order to benefit from their properties, which cannot be achieved with identical bulk materials. The development of new noble metal nanoparticles with USP is a constant goal in Nanotechnology, with the objective to obtain increasingly predictable final properties of nanoparticles.

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Section: Au/fe 2 O 3 Nanoparticlesmentioning

confidence: 99%

“…There are also possibilities of using an intermediate layer between the metal and oxide, made with functional groups (citrates, thiols, amines, etc. ), enabling the continuous Au shell growth [78,83,85,91].…”

Section: Au/fe 2 O 3 Nanoparticlesmentioning

confidence: 99%

Advances in Ultrasonic Spray Pyrolysis Processing of Noble Metal Nanoparticles—Review

Majerič

Rudolf

2020

Materials

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“…Besides silica, decoration of MNPs with noble metals (gold or silver) enables new properties such as optical properties and enhanced bioaffinity, biocompatibility, chemical and physical properties, without affecting the magnetic features of the core. Thus, gold nanoparticles (AuNPs) are widely used for surface coverage of Fe 3 O 4 ; several papers report the application of AuNPs@Fe 3 O 4 in electrochemical (bio)sensing, separation of biological structures, targeted delivery of drugs and bioimaging [7].…”

Section: Functionalization and Stabilization Of Magnetic Nanoparticlesmentioning

confidence: 99%

“…The synthesis protocol influences the final properties of MNPs. The most important properties of MNPs that can be exploited for medical applications are superparamagnetism, high magnetic moment, magnetocaloric effect, small particle size and large specific surface area that can be easily functionalized [7][8][9][10][11][12]. The magnetic properties are related to the core of the MNPs; therefore, the superparamagnetism effect depends on the nanoparticle size and is generally observed for the MNPs with the size dimension up to 100 nm.…”

Section: Introductionmentioning

confidence: 99%

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

2019

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During the last few decades, magnetic nanoparticles have been evaluated as promising materials in the field of cancer detection, screening, and treatment. Early diagnosis and screening of cancer may be achieved using magnetic nanoparticles either within the magnetic resonance imaging technique and/or sensing systems. These sensors are designed to selectively detect specific biomarkers, compounds that can be related to the onset or evolution of cancer, during and after the treatment of this widespread disease. Some of the particular properties of magnetic nanoparticles are extensively exploited in cancer therapy as drug delivery agents to selectively target the envisaged location by tailored in vivo manipulation using an external magnetic field. Furthermore, individualized treatment with antineoplastic drugs may be combined with magnetic resonance imaging to achieve an efficient therapy. This review summarizes the studies about the implications of magnetic nanoparticles in cancer diagnosis, treatment and drug delivery as well as prospects for future development and challenges of magnetic nanoparticles in the field of oncology.

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“…Aptamers have excellent molecular recognition abilities that make them uniquely suited for drug delivery, diagnostic, and therapeutic applications [9,10]. Using systematic evolution of ligands by exponential enrichment (SELEX), DeRosa et al developed and studied different aptamers for a variety of molecular targets, including neurotransmitters, cancer biomarkers, and viruses [11,12], and further developed aptamer-based MRI and computed tomography (CT) contrast agents by conjugating the aptamers and the contrast agents (as seen in Figure 1) for detection of intercranial thrombus in neurotraumatic patients [13,14]. Current research efforts are focused on developing new aptamer-based contrast agents to image fibrin in attempts to localize intercranial blood clots for early detection, as clinical treatment options for intercranial blood clots and prevention of their complications are highly dependent on early detections [15].…”

Section: Contrast Agentsmentioning

confidence: 99%

Advancements in Canadian Biomaterials Research in Neurotraumatic Diagnosis and Therapies

Chen

Auriat

et al. 2019

Processes

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Development of biomaterials for the diagnosis and treatment of neurotraumatic ailments has been significantly advanced with our deepened knowledge of the pathophysiology of neurotrauma. Canadian research in the fields of biomaterial-based contrast agents, non-invasive axonal tracing, non-invasive scaffold imaging, scaffold patterning, 3D printed scaffolds, and drug delivery are conquering barriers to patient diagnosis and treatment for traumatic injuries to the nervous system. This review highlights some of the highly interdisciplinary Canadian research in biomaterials with a focus on neurotrauma applications.

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Synthesis, transfer, and characterization of core-shell gold-coated magnetic nanoparticles

Abstract: Graphical abstract

Cited by 39 publications

References 41 publications

Advances in Ultrasonic Spray Pyrolysis Processing of Noble Metal Nanoparticles—Review

Advances in Ultrasonic Spray Pyrolysis Processing of Noble Metal Nanoparticles—Review

Implication of Magnetic Nanoparticles in Cancer Detection, Screening and Treatment

Advancements in Canadian Biomaterials Research in Neurotraumatic Diagnosis and Therapies

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