Synthesized phosphorylated and aminated derivatives of fucoidan and their potential antioxidant activity in vitro

Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death

“…Anticoagulant, antiviral, antitumor, anti-complement, immunomodulatory, anti-inflammatory, and antioxidant activities have been reported (Wang et al, 2009;Changotade et al, 2008;Li et al, 2008). Fucoidan is also known to promote tissue regeneration.…”

Synthesis of selenium-containing polysaccharides and evaluation of antioxidant activity in vitro

“…No obvious difference was observed between ASP and SeASP 2 in all concentrations. It was reported that the effect of antioxidant was due to their hydrogen donating ability [26]. The presence of OSeO 2 H groups in the SeASP 2 molecule could activate the hydrogen atom of the anomeric carbon.…”

Neuroprotective Effect of Fucoidan on H2O2-Induced Apoptosis in PC12 Cells Via Activation of PI3K/Akt Pathway

“…This oxidative damage can lead to mitochondrial dysfunction and apoptosis in neuronal cells (Heo et al 2009). Although a living system possesses several natural defense mechanisms, such as enzymes and antioxidant nutrients, which arrest the chain reaction of reactive oxygen species (ROS) initiation and production, these substances are unable to prevent the damage completely (Wang et al 2009). Especially, the brain is vulnerable to oxidative stress damage because of its high energy use, low levels of endogenous scavengers, high metabolic demands, extensive axonal and dendritic networks, and high cellular content of lipids and proteins (Mattson 2001).…”