Synthetic, spectral, thermal and antimicrobial studies of bis(N,N‐dialkyldithiocarbamato)arsenic(III) and antimony(III) complexes with diphenyldithiophos‐phate and diphenyldithiophosphinate

Abstract

31 P)] and thermal (TG, DTA and DSC) analysis. The TG analysis shows single-step decomposition of the complex to Sb 2 S 3 . These complexes have been screened for antibacterial and antifungal activity using the disc diffusion method. All the complexes have shown good activity as antibacterial and antifungal agents, which increased on increasing the concentration. Chloroamphenicol and terbinafin were used as standards for the comparison.herein some new mixed bis(dialkyldithiocarbamato)antimony(III) complexes with diphenyldithiophosphate and diphenyldithiophosphinate with their spectral, thermal and antimicrobial studies. EXPERIMENTAL Materials and methodsSodium/ammonium dialkyldithiocarbamates (E. Merck/ Fluka) were used as received. Antimony trichloride (E. Merck) was distilled before use. Arsenic trichloride was synthesized 24 and used after distillation. The reactants, such as ammonium diphenyldithiophosphate, 25 sodium diphenyldithiophosphinate 26 and bis(dialkyldithiocarbamato)antimony(III) chloride, 27 were prepared using previously reported methods. Solvents (benzene, acetone, hexane, diethyl ether, alcohols, etc.) were purified and dried by standard methods 28 before use. Melting points were determined in sealed capillary tubes. Physical measurementsMelting points (only for solid compounds) were determined on a B10 tech India melting point apparatus and are uncorrected. Arsenic and antimony were estimated Studies of bis(N,N-dialkyldithiocarbamato)arsenic(III) and antimony(III) 407 s = singlet, t = triplet, q = quartet and m = complex pattern. a A = (Me 2 NCS 2 ) 2 SbS 2 P(OC 6 H 5 ) and B = (Et 2 NCS 2 ) 2 SbS 2 P(OC 6 H 5 ). b Exo., exothermic process; endo., endothermic process.

Synthetic, spectral, thermal and antimicrobial studies on some bis(N,N′‐dialkyldithiocarbamato) antimony(III) alkylenedithiophosphates

“…The IR [ν(C C-N), ν(C S) and ν(P S)] and 31 P NMR data indicate that these complexes have similar molecular structure to bis(N,N-dialkyldithiocarbamato)Sb(III) diphenyldithiophosphate. 26 Hence, distorted octahedral geometry, with a stereochemically active lone pair of electrons occupying one of the triangular face of the octahedra has been tentatively proposed for these complexes (Fig. 1).…”

“…10,26,33 The electronic spectra of these newly synthesized antimony complexes exhibited three bands. In all the antimony complexes, the π -π * and n-π * transition are due to dithiophosphate moieties and π -π * intramolecular charge transfer transitions due to dithiocarbamate moieties 26 overlap and exhibit the most intense broad band in the range 230-280 nm. The second band appears as a shoulder (305-309 nm) and is assigned to the π -π * transition in the N C S (dithiocarbamate) group.…”

“…The second band appears as a shoulder (305-309 nm) and is assigned to the π -π * transition in the N C S (dithiocarbamate) group. 26 The third band of low intensity at 345-359 nm is attributed to n-π * or charge transfer transition due to dithiocarbamate moiety.…”

Insights into the Antimicrobial Potential of Dithiocarbamate Anions and Metal-Based Species

“…Overall, the compounds with L 55 showed better inhibition towards the bacterial strains tested (S. aureus, B. subtilis, E. coli, and P. aeruginosa) compared to those with L 56 . Chauhan et al also studied the antimicrobial properties of arsenic(III) and antimony(III) dithiocarbamates against four bacterial strains (S. aureus, B. subtilis, E. coli, and P. aeruguinosa) and two fungal species (A. niger and T. reesie) [108][109][110]. The investigated mono-nuclear compounds were [Sb(L 18,55 ) 2 ]X for X = O(O=)CMe, O(O=)CPh, O(S=)CMe, SCH 2 COOH, O(O=)CC 6 H 4 (OH), S(n-Pr), and OPh [109,110]; [M(L 18,55 ) 2 ] 2 X, for M(III) = As and Sb, X = -SCH 2 CH 2 S- [108,109], and M(L 55,56,65 ) 2 [S(S)P(Y) 2 ] for M(III) = As and Sb; Y = OPh and Ph [110].…”

Preparation, spectroscopic, thermal and powder X‐ray diffraction characterization, and antimicrobial activities of mixed bis(O,O′‐diisopropyldithiophosphato‐S,S′)antimony(III) derivatives with some oxygen and sulfur donor ligands

“…Dialkyldithiophosphoric acids are widely used in analytical chemistry (in the instrumental determination of metals and in extraction and complexation) . These types of derivatives show activity against various bacterial and fungal species and have been examined for their antimicrobial activities using the well diffusion method. The free ligands as well as their metal complexes were tested in vitro against four bacterial species (Gram‐positive Staphylococcus aureus (ATCC 9144) and Bacillus subtilis (ATCC 6051) and Gram‐negative Escherichia coli (ATCC 9637) and Pseudomonas aeruginosa (ATCC 25619)) and two plant fungal species ( Aspergillus niger (ATCC 9029) and Trichoderma reesei (ATCC 164)).…”