Systematic review of studies reporting perioperative and functional outcomes following male-to-female gender assignment surgery (MtoF GAS): a call for standardization in data reporting

Cocci, Andrea; Frediani, D.; Cacciamani, Giovanni; Cito, Gianmartin; Rizzo, Michele; Trombetta, Carlo; Vedovo, Francesca; Caroassai, S.; Rose, A. Delle; Matteucci, Valeria; Rosi, Francesco; Buccianti, P; Ceccarelli, Cristina; Russo, Giorgio Ivan; Polloni, G.; Serni, Sergio; Gacci, Mauro; Carini, Marco; Minervini, Andrea; Morelli, Girolamo

doi:10.23736/s0393-2249.19.03407-6

Cited by 11 publications

(15 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(7) However, our mean scores (25.8 vs 18.6) are in line with the average FSFI mean score reported in the literature with a range from 18.7 to 23.4. (11) The age difference favoring the NCP group could be a bias that should be taken into account and that suggests caution in reaching a conclusion from our results. In spite of this, in other cohorts of transgender women reported in the literature, sexual function was negatively associated with years since surgery, but not with age.…”

Section: Discussionmentioning

confidence: 80%

Neoclitoris location may affect sexual function in transgender women: a pelvic MRI study.

Vedovo

Pavan²,

Bertolotto

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

Natal women with anorgasmia possess a smaller clitoral glans and clitoral components farther from the vagina lumen than women with normal orgasmic function. There are no studies evaluating this correlation in operated transgender women. We evaluated whether differences in magnetic resonance imaging (MRI) measurements of neoclitoris volume and distance between the neoclitoris and the neo-vagina were correlated with differences in sexual function. We recruited for a prospective survey study 40 operated male to female patients (oMtF) who had undergone gender affirming surgery (GAS), using two different techniques, the pubic neoclitoris technique (PNT) and the neourethroclitoroplasty according to Petrović (NCP), and postoperative pelvic MRI. Individual pelvic MRIs were reviewed by two blinded investigators, the three axes of the neoclitoris were measured and the volume was calculated using the ellipsoid formula. The distance between the neoclitoris and the neovagina was also measured. Sexual functioning was assessed using the Female Sexual Function Index (FSFI) and the operated Male to Female Sexual Function Index (oMtFSFI). Mean scores differences in FSFI, oMtFSFI were examined; associations with clitoral size, location, sexual functioning and demographical variables were investigated as well. The response rate was 55%, 11 oMtFs were operated with PNT and 11 with NCP. The PNT group presented a neo-clitoris mean volume of 1.04 cc vs 1.31 cc of the other group (p = 0.55). The mean distance between neo-clitoris and neovagina was 4.20 cm in the PNT group and 2.55 in the NCP group (p < 0.001). Patients who had undergone NCP achieved a higher FSFI and oMtFSFI mean Total Score than those operated with the previous used PNT (FSFI 25.8 vs 18.6 p = 0.08; oMtFSFI 23.36 vs 27.18 p > 0.20). According to pelvic MRI measurements, this study suggests a correlation between neoclitoris location and operated male to female sexual satisfaction.

show abstract

Section: Discussionmentioning

confidence: 80%

Neoclitoris location may affect sexual function in transgender women: a pelvic MRI study.

Vedovo

Pavan²,

Bertolotto

et al. 2022

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…better understanding of outcomes after PIV and other gender affirming surgeries 21 . Second, urinary complications were pooled based on the reported complication rate in the articles and zero-event studies were excluded if the outcome was not mentioned.…”

Section: Ding Et Al Urinary Complications After Penile Inversion Vagi...mentioning

confidence: 99%

Urinary complications after penile inversion vaginoplasty in transgender women: Systematic review and meta-analysis

Ding

Khondker

Goldenberg

et al. 2022

CUAJ

View full text Add to dashboard Cite

Introduction: Penile inversion vaginoplasty (PIV) remains the gold standard technique for vaginoplasty, a gender-affirming feminizing surgery, but has been associated with urinary complications; however, there is little literature synthesizing urinary complications after PIV surgery, and there is a need to compile these complications to counsel patients pre- and postoperatively on managing surgical expectations. In this systematic review, we summarize the prevalence of urinary complications following PIV. Methods: We searched the MEDLINE, EMBASE, CINAHL, and Scopus databases in July 2020. The primary outcome was the prevalence of urinary and surgical complications in patients after penile inversion vaginoplasty. Pooled prevalence was determined from extrapolated data. ROBINS-I tool was used to assess study quality. The study was prospectively registered on PROSPERO (CRD42020204139). Results: Of 843 unique records, 27 articles were pooled for synthesis, with 3388 patients in total. Overall patient satisfaction ranged from 80–100%. The most common urological complications included poor/splayed stream (11.7%, 95% confidence interval [CI] 5.7–19.3), meatal stenosis (6.9%, 95% CI 2.7–12.7), and irritative symptoms (frequency, urgency, nocturia) (11.5%, 95% CI 2.6–25.1). Other urinary complications included retention requiring catheterization (5.1%, 95% CI 0.3–13.8), incontinence (8.7%, 95% CI 3.4–15.6), urethral stricture (4.6%, 95% CI 1.2–9.8), and urinary tract infection (5.6%, 95% CI 2.7–9.4). Most pooled studies had moderate risk of bias. Conclusions: The available evidence suggests that there is a low prevalence of urinary complications following PIV. Overall, there is a need for standardization of data in transgender surgical care to better understand surgical outcomes and improve postoperative management.

show abstract

“…Some attempts at synthesising the literature exist 10–12 ; however, these systematic reviews focus on certain facets of TRS such as surgical outcomes, 10 outcomes of specific surgical techniques 11 13 14 or narrow demographic samples (eg, trans females). 15 As research about TRS is emergent, a systematic scoping review would help provide a comprehensive examination of the current landscape of TRS research. 16 Furthermore, a broad review of the TRS literature will allow for categorisation of the current literature and help understand the strengths of the TRS literature.…”

Section: Introductionmentioning

confidence: 99%

“…Nonetheless, despite the increase in TRS surgery, the literature around TRS is still in its infancy and the existing literature is varied (eg, includes literature on policies, surgical outcomes, patient experience). Some attempts at synthesising the literature exist10–12; however, these systematic reviews focus on certain facets of TRS such as surgical outcomes,10 outcomes of specific surgical techniques11 13 14 or narrow demographic samples (eg, trans females) 15. As research about TRS is emergent, a systematic scoping review would help provide a comprehensive examination of the current landscape of TRS research 16.…”

Section: Introductionmentioning

confidence: 99%

Protocol for a scoping review on transition-related surgery procedures, outcome measures and access to care

et al. 2022

View full text Add to dashboard Cite

IntroductionTransgender and gender diverse (TGD) individuals often identify with a gender different to the one assigned at birth. Transition is a term used to describe the process TGD individuals take to live as their true gender. Surgery can be a very important aspect of care for members of TGD communities. Transition-related surgery (TRS) refers to many different types of surgeries completed to meet a TGD individual’s gender-related goals. While various systematic reviews have attempted to synthesise the existing peer-reviewed literature around aspects of TRS, there are few scoping reviews in this area. Our scoping review aims to address this gap through providing an up-to-date overview of the TRS literature in order to provide an overarching view of the topic.Method and analysisThis review will follow the methods outlined by the Joanna Briggs Institute’s methodology for scoping reviews and will be reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. A search of nine scientific databases resulted in 20 062 potential articles. After removing duplicates, articles will be screened for inclusion using Covidence. Data extraction and synthesis will be carried out using NVivo and reviewed by team members.Ethics and disseminationAs this study is a scoping review of the existing literature, no ethics review is required. The findings from this review will be disseminated through multiple pathways including open access publication, submission to conferences, social media and Listservs. The findings of the study will also be readily available to clinicians, organizations, interest groups, and policy-makers.

show abstract

Systematic review of studies reporting perioperative and functional outcomes following male-to-female gender assignment surgery (MtoF GAS): a call for standardization in data reporting

Cited by 11 publications

References 30 publications

Neoclitoris location may affect sexual function in transgender women: a pelvic MRI study.

Neoclitoris location may affect sexual function in transgender women: a pelvic MRI study.

Urinary complications after penile inversion vaginoplasty in transgender women: Systematic review and meta-analysis

Protocol for a scoping review on transition-related surgery procedures, outcome measures and access to care

Contact Info

Product

Resources

About