Targeted Delivery with Carbon Nanotubes

Eco-friendly synthesis of carbon nanotubes and their cancer theranostic applications

“…The salient advantageous features for CNT-based drug delivery systems encompass pH-dependent behavior, specificity/selectivity, prolonged/controlled release features, reduced side effects, high drug loading capacity, and reduced administration dose/frequency. 137 These materials with their unique architectures have been explored for targeted delivery of anticancer and chemotherapeutic agents (Table 5); 138 the improved release behavior and multifunctionality could be attained especially by MWCNTs for cancer therapy and diagnosis owing to sustained drug release in related cancer tissues and high surface areas for functioning groups. In addition, pH sensitive polymers ( e.g.…”

MacGyvered Multiproperty Materials Using Nanocarbon and Jam: A Spectroscopic, Electromagnetic, and Rheological Investigation

“…Carbon structures as filler materials are currently proposed in several fields of application—for instance, to reinforce metals [ 36 ], carbon fiber polymer composites [ 37 ], and polylactide (PLA) [ 38 ]. Moreover, their use in the medical field has been investigated—CNTs and graphene have been extensively studied for use in drug delivery systems [ 39 , 40 , 41 ] and tissue engineering [ 42 , 43 , 44 ]; moreover the electrical properties of CNTs have been applied to connect neuronal cells [ 45 ].…”

Novel optimized biopolymer-based nanoparticles for nose-to-brain delivery in the treatment of depressive diseases

“…The CNT therapeutic experiments, for the majority in the preclinical stage, started no more than 20 years ago: nevertheless, many attempts have been carried out in gene peptide and drug delivery [22][23][24][25][26][27] for many applications, such as cancer, lymphatic, ocular and brain targeting. About brain targeting, many results have been reached, such as the reactivation of neuronal pathway aer brain injury, 28,29 and the delivery of drugs 22,30 passing through the BBB. Even though the BBB passing was demonstrated by the gastrointestinal way, a potential uptake of pristine MWCNT from other organs through the blood torrent could occur, inducing side effects or toxicity in other not targeted organs.…”