Abstract:Numerous antibacterial
biomaterials have been developed, but a
majority of them suffer from poor biocompatibility. With the purpose
of reducing biomaterial-related infection and cytotoxicity, friction
stir processing (FSP) was employed to embed silver nanoparticles (Ag
NPs) in a Ti–6Al–4V (TC4) substrate. Characterization
using scanning electron microscopy, transmission electron microscopy,
and three-dimensional atom probe tomography illustrates that NPs are
distributed more homogeneously on the surface of TC4… Show more
“…Copyright 2019, Elsevier) and b) typical Staphylococcus aureus ( S.a ) and Escherichia coli ( E.c ) colonies incubated on the samples after 24 h. The depth specifies the amout of Ag nanoparticles. (Reproduced with permission . Copyright 2018, ACS Publications).…”
Thanks to a considerable number of fascinating properties, titanium (Ti) and Ti alloys play important roles in a variety of industrial sectors. However, Ti and Ti alloys could not satisfy all industrial requirements; the degradation of Ti and Ti alloys always commences on their surfaces in service, which declines the performances of Ti workpieces. Therefore, with aim to further improve their mechanical, corrosion and biological properties, surface modification is often required for Ti and Ti alloys. This article reviews the technologies and recent developments of surface-modification methods with respect to Ti and Ti alloys, including mechanical, physical, chemical, and biochemical technologies. Conventional methods have limited improvement in the properties and/or restriction on the geometry of workpieces. Therefore, many advanced surfacemodification technologies have emerged in recent decades. New methods make Ti and Ti alloys have better performance and extended applications. With requirement of high surface properties in future. Understanding the mechanism in various surface-modification methods, combining the advantages of current technologies and developing new coating materials with high performance are required urgently. As such, incorporation of different surface-modification technologies with high-performance modified layers may be the mainstream of surface modifications for Ti and Ti alloys. . His current research interests focus on the metal additive manufacturing (e.g., selective laser melting, electron beam melting), titanium alloys and composites, and processing-microstructureproperties in high-performance materials.
“…Copyright 2019, Elsevier) and b) typical Staphylococcus aureus ( S.a ) and Escherichia coli ( E.c ) colonies incubated on the samples after 24 h. The depth specifies the amout of Ag nanoparticles. (Reproduced with permission . Copyright 2018, ACS Publications).…”
Thanks to a considerable number of fascinating properties, titanium (Ti) and Ti alloys play important roles in a variety of industrial sectors. However, Ti and Ti alloys could not satisfy all industrial requirements; the degradation of Ti and Ti alloys always commences on their surfaces in service, which declines the performances of Ti workpieces. Therefore, with aim to further improve their mechanical, corrosion and biological properties, surface modification is often required for Ti and Ti alloys. This article reviews the technologies and recent developments of surface-modification methods with respect to Ti and Ti alloys, including mechanical, physical, chemical, and biochemical technologies. Conventional methods have limited improvement in the properties and/or restriction on the geometry of workpieces. Therefore, many advanced surfacemodification technologies have emerged in recent decades. New methods make Ti and Ti alloys have better performance and extended applications. With requirement of high surface properties in future. Understanding the mechanism in various surface-modification methods, combining the advantages of current technologies and developing new coating materials with high performance are required urgently. As such, incorporation of different surface-modification technologies with high-performance modified layers may be the mainstream of surface modifications for Ti and Ti alloys. . His current research interests focus on the metal additive manufacturing (e.g., selective laser melting, electron beam melting), titanium alloys and composites, and processing-microstructureproperties in high-performance materials.
“…Here, silver nanoparticles placed in the preformed grooves on the surface of TC4 when subjected to FSP, they get homogenously distributed in the surface of TC4 matrix. The distribution profile of AgNPs is dependent on the depth of the preformed grooves [129,130]. On examination, it was observed that silver-rich NPs with a size ranging from 10 to 20 nm were diffused into the substrate.…”
Section: Surface Coating Using Ag-based Nanocompositesmentioning
confidence: 99%
“…TC4/Ag metal matrix nanocomposite is a potential nanocomposite that embeds AgNPs on a biomaterial surface for creating balance between the antibacterial effect and biocompatibility. The modified surface possesses an antibacterial properties [129,130].…”
Section: Surface Coating Using Ag-based Nanocompositesmentioning
Significant research and development in the field of biomedical implants has evoked the scope to treat a broad range of orthopedic ailments that include fracture fixation, total bone replacement, joint arthrodesis, dental screws, and others. Importantly, the success of a bioimplant depends not only upon its bulk properties, but also on its surface properties that influence its interaction with the host tissue. Various approaches of surface modification such as coating of nanomaterial have been employed to enhance antibacterial activities of a bioimplant. The modified surface facilitates directed modulation of the host cellular behavior and grafting of cell-binding peptides, extracellular matrix (ECM) proteins, and growth factors to further improve host acceptance of a bioimplant. These strategies showed promising results in orthopedics, e.g., improved bone repair and regeneration. However, the choice of materials, especially considering their degradation behavior and surface properties, plays a key role in long-term reliability and performance of bioimplants. Metallic biomaterials have evolved largely in terms of their bulk and surface properties including nano-structuring with nanomaterials to meet the requirements of new generation orthopedic bioimplants. In this review, we have discussed metals and metal alloys commonly used for manufacturing different orthopedic bioimplants and the biotic as well as abiotic factors affecting the failure and degradation of those bioimplants. The review also highlights the currently available nanomaterial-based surface modification technologies to augment the function and performance of these metallic bioimplants in a clinical setting.
“…Then, TiO 2 /TC4 composite coating, which provides a no biotoxicity environment for cells and promotes cell adhesion and proliferation, was produced [121]. Wang et al [122] produced a promising biomaterial−TC4/Ag metal matrix nanocomposite, which can achieve a balance between the antibacterial effect and biocompatibility. In Figure 20, with the increase of silver content, the number of staphylococcus aureus (S. aureus) cells decreased significantly and dead cells with an indistinct or deformed membrane were observed on 2 mm-Ag-FSP.…”
Section: Friction Stir Processingmentioning
confidence: 99%
“…In Figure 20, with the increase of silver content, the number of staphylococcus aureus (S. aureus) cells decreased significantly and dead cells with an indistinct or deformed membrane were observed on 2 mm-Ag-FSP. [122]. Reprinted with permission from reference [122] 2018 Elsevier.…”
With the increasing demand for bone implant therapy, titanium alloy has been widely used in the biomedical field. However, various potential applications of titanium alloy implants are easily hampered by their biological inertia. In fact, the interaction of the implant with tissue is critical to the success of the implant. Thus, the implant surface is modified before implantation frequently, which can not only improve the mechanical properties of the implant, but also polish up bioactivity and osseoconductivity on a cellular level. This paper aims at reviewing titanium surface modification techniques for biomedical applications. Additionally, several other significant aspects are described in detail in this article, for example, micromorphology, microstructure evolution that determines mechanical properties, as well as a number of issues concerning about practical application of biomedical implants.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
