Technological aspects of obtaining liquid extracts of black poplar buds and determining the strategy for their standardization at the pharmaceutical development stage

Bondar, Anna; Gubar, Svitlana; Smielova, Nataliia; Shyteyeva, Tatyana; Tkachenko, O. V.; Kryvoruchko, Liliia; Karpenko, Karina; Georgiyants, Victoriya

doi:10.15587/2519-4852.2020.197270

Cited by 1 publication

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“…Results showed that the concentration of the extracting and infusion time influence the qualitative composition of the extract. For obtaining an extract rich in hydroxycinnamic acids (57.70%), it is advisable to use ethanol (70%) and for flavonoids (82.60%), it is advisable to use ethanol (96%) [28].…”

Section: Phytochemical Composition Of Populus Nigra L Budsmentioning

confidence: 99%

Recent Advances Regarding the Phytochemical and Therapeutic Uses of Populus nigra L. Buds

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Avram

Pavel

et al. 2020

Plants

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Populus nigra L. (Salicaceae family) is one of the most popular trees that can be found in deciduous forests. Some particularities that characterize the Populus genus refer to the fact that it includes more than 40 species, being widespread especially in Europe and Asia. Many residues, parts of this tree can be used as a bioresource for different extracts as active ingredients in pharmaceuticals next to multiple benefits in many areas of medicine. The present review discusses the latest findings regarding the phytochemical composition and the therapeutic properties of Populus nigra L. buds. The vegetal product has been described mainly to contain phenolic compounds (phenols, phenolic acids and phenylpropanoids), terpenoids (mono and sesquiterpenoids), flavones (e.g., apigenol and crysin), flavanones (e.g., pinocembrin and pinostrombin), caffeic/ferulic acids and their derivates, and more than 48 phytocompounds in the essential oils. The resinous exudates present on the buds have been the major plant source used by bees to form propolis. Several studies depicted its antioxidant, anti-inflammatory, antibacterial, antifungal, antidiabetic, antitumor, hepatoprotective, hypouricemic properties and its effects on melanin production. All these lead to the conclusion that black poplar buds are a valuable and important source of bioactive compounds responsible for a wide range of therapeutic uses, being a promising candidate as a complementary and/or alternative source for a large number of health problems. The aim of the review is to gather the existing information and to bring an up to date regarding the phytochemical and therapeutic uses of Populus nigra L. buds.

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Section: Phytochemical Composition Of Populus Nigra L Budsmentioning

confidence: 99%