This study aims to identify the influence of attitude variables, subjective norms, religiosity, entrepreneurial knowledge, and demographic factors on entrepreneurial interest. The population of this study were all active students of IAIN Salatiga. While the number of samples used were 374 students. Multiple linear regression technique was applied in this study to analyze the data. The results obtained from this study are simultaneously all independent variables have a significant effect on the interest in entrepreneurship. While partially, the variables that have a positive and significant effect on interest in entrepreneurship are attitudes, subjective norms, entrepreneurial knowledge, study programs, and entrepreneurial experience. While the variables of religiosity, gender, age, entrepreneurship courses, and campus organization partially have no significant effect. The advice that can be given based on this research is that the IAIN Salatiga institution should continue to encourage students to grow interest in entrepreneurship, these efforts can be made through strengthening entrepreneurship courses and entrepreneurial training.