Terminalia catappa Linn.: A TREASURY OF PHARMACOLOGICAL BENEFITS

Abstract

Terminalia catappa Linn. belonging to family Combretaceae is well known plant due to its nutritional fruit, bark, leaves and roots which are having medicinal properties. The various phytochemicals which are present in it are such as gallic acid, ellagic acid, corilagin, alkaloid, flavonoid, protein, phytosteroids, phenol and carotenoids are isolated form the different parts of the plant in various solvent systems. These isolated compounds have found to be possess numerous pharmacological properties such as antioxidant, antidiabetic, antimicrobial, antifungal, antinociceptive, hepatitis treatment, hypocholesterolemia, immunomodulatory, anthelmintic, antiviral, antiaging, anti-inflammatory, anticancer, anti-tumor, hematological, anthelmintic, aphrodisiac, wound healing. These all pharmacological activities cumulatively enhanced its traditional value and uses. In this review paper, the different pharmacological activities and their benefits are explored which are exhibited by different phytoconstituents present in different parts of the plant.

T. Catappa confers an antioxidant effect to electrospun polyvinyl alcohol nanofibers

“…The evaluation of the qualitative chemical profile of the T. catappa extract used in this study has shown, among others, the presence of flavonoids such as quercetin, rutin, isoorientin, vitexin and isovitexin, as well as the presence of hydrolysable tannins such as gallic acid and ellagic acid, and also triterpenoid derivatives such as asian and ursolic acid (BOSCARATO et al, 2021;TERÇAS et al, 2017;VENKATALAKSHMI, P.;BRINDHA,2021;MININEL et al, 2014). These flavonoid and non-flavonoid polyphenols, abundant compounds derived from plant secondary metabolism, are related to the ability of medicinal plants to neutralize free radicals (MOHAMMED et al,2022), being attributed to them anti-inflammatory and antioxidant activities of T. catappa (YADAV et al, 2021;IHEAGWAM et al, 2022).…”

“…Native to Southeast Asia (NUGROHO et al, 2019), it was introduced and naturalized worldwide by tropical and subtropical regions (RAVI, 2020). Hydrolysable tannins are the major compounds responsible for the therapeutic activities of this species; as a broad-spectrum antimicrobial effect (YADAV et al, 2021;EL-RAFIE;EL-RAFIE;ZAHRAN, 2017;DARMAWATI et al,2022;BOSCARATO et al,2021), antifungal (TERÇAS et al, 2017), antioxidant (YADAV et al, 2021IHEAGWAM et al, 2022;DIVYA et al, 2019), antinociceptive and anti-inflammatory (RAVI, 2019) that arouse interest in the potential benefit to skin healing.…”