Testicular non-Hodgkin's lymphoma presenting in a young adult

Ratkal, Vishal; Chawla, Arun; Mishra, Dilip Kumar; Monappa, Vidya

doi:10.1136/bcr-2014-208633

Cited by 9 publications

(16 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, there are four reports 3,12,14,18 of testicular lymphoma presenting as epididymo-orchitis. In another report by Mazzu et al, 11 one patient had enlarged hypervascular epididymis but the presence of epididymal inflammation without histological correlation was suggested.…”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6] Familiarity with US features of testicular lymphoma will help to differentiate lymphoma from other germ cell tumours or inflammation and provide appropriate management. Since reports of US features of testicular lymphoma remain limited, 3,[7][8][9][10][11][12][13][14][15][16][17][18][19] we reviewed the clinical presentation and US features of testicular lymphoma at our institution to add to the current knowledge.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Testicular Lymphoma: Clinical and Imaging Features

Pattamapaspong¹,

Khomarwut²,

Ya-In³

et al. 2016

Hong Kong J Radiol

View full text Add to dashboard Cite

Objective: To review the clinical presentation and imaging features of testicular lymphoma. Methods: We retrospectively reviewed the clinical data, and grey-scale and colour Doppler ultrasound features of 11 patients with proven testicular lymphoma between January 2000 and September 2013. The patients were aged 35 to 84 years (mean, 59 years). The diagnosis was established by orchidectomy in eight patients, by compelling evidence including bone marrow and lymph node biopsy in two, and autopsy in one. Results: Of the 11 patients, seven presented with painless scrotal mass(es), three presented with an afebrile painful scrotal mass, and one presented with a febrile painful scrotal mass. Disease was unilateral in nine patients and bilateral in two. Primary testicular lymphoma was diagnosed in six patients and secondary testicular lymphoma in five, of which nine were non-Hodgkinʼs lymphoma with diffuse large B-cell lymphoma (DLBCL) and two were T-cell lymphoma. Ultrasonography revealed diffuse hypoechoic involvement in seven patients, a solitary hypoechoic mass in two patients, and bilateral multiple hypoechoic masses in two patients. All lesions showed hypervascularity. Enlarged epididymis with hypervascularity was present in two patients mimicking epididymoorchitis. Conclusion: Testicular lymphoma is predominantly DLBCL. Patients may present with painless or painful scrotal mass(es). Lymphoma should be considered in a man older than 50 years who presents with testicular mass regardless of pain with focal or diffuse hypervascular hypoechoic testicular lesion(s) on ultrasound. The associated hypervascular enlarged epididymis does not exclude the diagnosis of testicular lymphoma.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Testicular Lymphoma: Clinical and Imaging Features

Pattamapaspong¹,

Khomarwut²,

Ya-In³

et al. 2016

Hong Kong J Radiol

View full text Add to dashboard Cite

show abstract

“…The most common clinical manifestation of this entity is a unilateral painless testicular swelling, with a frequent vascular invasion, epididymis and cord involvement [9]. The disease tends to relapse promptly after initial management involving orchiectomy and chemoradiotherapy [10].…”

Section: Discussionmentioning

confidence: 99%

Primary T-Cell Lymphoma of the Testis Presenting in a Young Adult

Bendari¹,

Matrane²,

Qachouh³

et al. 2021

Health Sci

View full text Add to dashboard Cite

We report the case of a 40-year-old male presented with a painless right testicular swelling. Right radical orchidectomy was performed. The pathological diagnosis was peripheral T-Cell lymphoma-not otherwise specified (PTCL-NOS). According to Ann Arbor staging, the initial clinical stage was IEa. Treating him with four courses of the CHOEP protocol and intrathecal prophylactic chemotherapy was unsuccessful; with the appearance of orbital infiltration and a loco-regional extension. Although the patient started a second line chemotherapy, he unfortunately succumbed to death.

show abstract

“…6 It is well-known that testicular lymphoma is more common among patients over 60 years of age, and rarely encountered in younger patients. 7 Secondary testicular lymphoma is more common in patients under 60 years of age and bilateral testicular involvement is more common. Bertalotto et al reported that 75% of 43 patients with testicular lymphoma were over the age of 60 at the time of diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Diffuse Large B-cell Lymphoma of Testis: a Case Report and Current Literature Review

Güler

Üçpınar

Erbin

2020

View full text Add to dashboard Cite

Introduction: Testicular cancers detected in older males are mostly testicular lymphomas. Primary testicular lymphoma (PTL) is a rare, clinically aggressive form of extranodal lymphoma. In population-based studies, the  incidence of PTL is 0.09-0.26/100.000. The vast majority of PTL are diffuse large B-cell lymphoma (DLBCL).   Case presentation: We present a case of PTL diagnosed in a 68-year-old male patient and also, we discuss the incidence, clinical presentation, prognostic factors and management of this rare pathology in the light of current literature. Histopathological and immunohistochemical exams of the patient confirmed the diagnosis of DLBCL after radical orchiectomy. According to the internal prognostic index (IPI), patients’ IPI score was evaluated as 5 and according to Ann Arbor staging, patients’ stage was interpreted as grade 3E. Cyclophosphamide, vincristine, etoposide, and prednisolone chemotherapy was planned for the patient and until now, the patient received his first chemotherapy regimen.   Discussion: Primary testicular lymphoma should be kept in mind for every patient who admits with a testicular mass, especially in advanced age.  Misinterpreatation of the clinical findings can delay the definitive diagnosis. Primary testicular lymphoma should be managed with a multi-disciplinary team including urologists, medical and radiation oncologists. 

show abstract

Testicular non-Hodgkin's lymphoma presenting in a young adult

Cited by 9 publications

References 8 publications

Testicular Lymphoma: Clinical and Imaging Features

Testicular Lymphoma: Clinical and Imaging Features

Primary T-Cell Lymphoma of the Testis Presenting in a Young Adult

Diffuse Large B-cell Lymphoma of Testis: a Case Report and Current Literature Review

Contact Info

Product

Resources

About