Testicular Rupture or Testicular Fracture? A Case Report and Literature Review

Addas, Firas A.; Yan, Sylvia; Hadjipavlou, Marios; Gonsalves, Michael; Sabbagh, Samer

doi:10.1155/2018/1323780

Cited by 5 publications

(6 citation statements)

References 14 publications

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“…Testicles are predisposed to traumatic injuries because of their external location. Testicular trauma should be treated as an emergency condition because exposure of the spermatic antigen to the immune system [199] may induce an auto-immune response against sperm through the production of anti-sperm antibodies (ASA) [200]. Among infertile males, 8-21% have ASA that can negatively affect sperm motility, capacitation, and acrosome [201].…”

Section: Testicular Traumamentioning

confidence: 99%

The Role of Stem Cells and Their Derived Extracellular Vesicles in Restoring Female and Male Fertility

Qamar

Hussain

Rafique

et al. 2021

Cells

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Infertility is a globally recognized issue caused by different reproductive disorders. To date, various therapeutic approaches to restore fertility have been attempted including etiology-specific medication, hormonal therapies, surgical excisions, and assisted reproductive technologies. Although these approaches produce results, however, fertility restoration is not achieved in all cases. Advances in using stem cell (SC) therapy hold a great promise for treating infertile patients due to their abilities to self-renew, differentiate, and produce different paracrine factors to regenerate the damaged or injured cells and replenish the affected germ cells. Furthermore, SCs secrete extracellular vesicles (EVs) containing biologically active molecules including nucleic acids, lipids, and proteins. EVs are involved in various physiological and pathological processes and show promising non-cellular therapeutic uses to combat infertility. Several studies have indicated that SCs and/or their derived EVs transplantation plays a crucial role in the regeneration of different segments of the reproductive system, oocyte production, and initiation of sperm production. However, available evidence triggers the need to testify the efficacy of SC transplantation or EVs injection in resolving the infertility issues of the human population. In this review, we highlight the recent literature covering the issues of infertility in females and males, with a special focus on the possible treatments by stem cells or their derived EVs.

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Section: Testicular Traumamentioning

confidence: 99%

The Role of Stem Cells and Their Derived Extracellular Vesicles in Restoring Female and Male Fertility

Qamar

Hussain

Rafique

et al. 2021

Cells

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“…In one report, 28% of testicular injuries from trauma also presented with associated perineal soft tissue injuries. Although in general a rare entity in blunt trauma situations, testicular trauma is often associated with motorcycle collisions (3,4). These are usually assumed to be from contact with the fuel tank, which strikes the groin and results in damage to the scrotum and perineum, commonly called a fuel tank injury (3,5).…”

Section: Functional Castration From Blunt-force Trauma To Motorcycle Gas Tank From a Car Versus Motorcycle Mvamentioning

confidence: 99%

Functional Castration from Blunt-force Trauma to Motorcycle Gas Tank from a Car-versus-motorcycle MVA

Garcher

2019

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We present a case of bilateral testicular rupture with significant extrusion and seminiferous tubule loss in an otherwise healthy 26-year-old male as the result of a car-versus-motorcycle accident. The patient was the lone driver of a motorcycle that was T-boned, resulting in significant scrotal trauma necessitating operative intervention. Because of this, he developed subsequent severe hypogonadism, which improved with exogenous testosterone administration. We undertook a literature review, which revealed that blunt trauma is an extremely uncommon cause of acquired hypogonadism.

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“…However, the presentation of symptoms is often non-specific and generalized to the pelvic region, especially in the context of other pelvic injuries, which can result in delayed presentation and mislead diagnostic prioritization [ 3 , 5 ]. Nonetheless, ultrasonography has been found to maintain the highest degree of diagnostic sensitivity and accuracy when evaluating testicular pathologies, including testicular rupture [ 2 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…Motorcycle collisions specifically are associated with an increased risk of testicular trauma and rupture [1]. Testicular rupture is characterized as disruption of the surrounding tunica albuginea [2][3][4]. However, the presentation of symptoms is often nonspecific and generalized to the pelvic region, especially in the context of other pelvic injuries, which can result in delayed presentation and mislead diagnostic prioritization [3,5].…”

Section: Introductionmentioning

confidence: 99%

Testicular Rupture Following Motorcycle Accident

Eldore,

Borries,

Malick

et al. 2023

Cureus

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Testicular rupture is a surgical emergency necessitating prompt diagnosis and intervention to prevent irreversible damage. Blunt trauma, including motorcycle collisions, is a common cause of testicular rupture. In the case of multi-trauma, the diagnosis of testicular rupture may be missed in the rush to surgical intervention of more grossly obvious injuries. We present a case of a 24-year-old male who suffered a motorcycle accident and subsequently presented with diffuse abdominal and hip pain. Physical exam and imaging at the emergency department showed multiple pelvic bone fractures, along with a small scrotal injury which was triaged below his pelvic injuries. His pelvic fractures were immediately operated on. Nearly 18 hours after his initial presentation, the patient received a scrotal ultrasound which demonstrated a rupture of the right testicle. Due to this long delay in diagnosis, his urological team opted for non-surgical management and instead employed a more conservative treatment regimen involving pain control, scrotal support, rest, and serial scrotal ultrasounds. This case highlights the importance of timely ultrasound examination for testicular pathology in the setting of multi-trauma and known scrotal injury. Another highlight of this case is the showcase of an uncommon treatment regimen utilizing conservative tactics as opposed to opting for surgical intervention.

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Testicular Rupture or Testicular Fracture? A Case Report and Literature Review

Cited by 5 publications

References 14 publications

The Role of Stem Cells and Their Derived Extracellular Vesicles in Restoring Female and Male Fertility

The Role of Stem Cells and Their Derived Extracellular Vesicles in Restoring Female and Male Fertility

Functional Castration from Blunt-force Trauma to Motorcycle Gas Tank from a Car-versus-motorcycle MVA

Testicular Rupture Following Motorcycle Accident

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