Testosterone, Growth Hormone and IGF-I Responses to Acute and Chronic Resistive Exercise in Men Aged 55-70 Years

Nicklas, Barbara; Ryan, Anthony J.; Treuth, M. M.; Harman, S. Mitchell; Blackman, Marc R.; Hurley, Ben F.; Rogers, M. A.

doi:10.1055/s-2007-973035

Cited by 112 publications

(73 citation statements)

References 11 publications

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“…Exercise training has been shown to induce either signi®-cant changes 32 or no modi®cation 11,33 in gonadal and adrenal androgen levels in nondiabetic and diabetic men. Our results show an increase in DHEA levels induced by training, and an inverse relationship between changes in DHEA levels and changes in triglyceride and the sum of LDL and VLDL levels.…”

Section: Discussionmentioning

confidence: 99%

Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes

et al. 2001

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OBJECTIVE:To investigate the effect of an exercise training program on lipid pro®le in correlation with DHEA level and body weight and body composition in type 2 diabetic men. DESIGN: Longitudinal, controlled clinical intervention study with exercise training consisting of an 8 week supervised program of aerobic exercise (75% VO 2 peak, 45 min), twice a week and intermittent exercise, once a week, on a bicyle ergometer. SUBJECTS: Sixteen men (age 45.4 AE 7.2 y (mean AE s.d.), HbA1c 8.15 AE 1.7%, body mass index (BMI) 29.6 AE 4.6 kgam 2 ) were randomly divided into two groups: trained group (n 8) and control group (n 8 P`0.001), and DHEA levels (11.00 AE 3.10 vs 14.25 AE 4.10 nmolal, P`0.05) with no modi®cation in body weight. Changes in triglycerides were negatively correlated with changes in DHEA (r À0.81, P 0.03). This correlation was independent of changes in abdominal fat distribution. CONCLUSION: Training decreases abdominal fat depots, improves muscular mass and affects favourably triglyceride and DHEA levels. Changes in triglycerides and DHEA were inversely related.

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Section: Discussionmentioning

confidence: 99%

Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes

et al. 2001

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“…Exercise studies comparing single-and multiple-set protocols differ not only with respect to training volume but also with respect to the equipment used for the measurements (9,25,31,41), exercise intensity (6,30,31,34), exercise mode (i.e., velocity [30,39,41]), periodization strategy (28,30,41), work until failure or not (22), and muscle groups (32,38). Also, the training experiences of the subjects investigated in these studies were very heterogeneous, ranging from untrained subjects to top-division footballers (25).…”

Section: Introductionmentioning

confidence: 99%

Effects of Single- vs. Multiple-Set Resistance Training on Maximum Strength and Body Composition in Trained Postmenopausal Women

Kemmler¹,

Lauber²,

Engelke³

et al. 2004

J Strength Cond Res

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ABSTRACT. Kemmler, W.K., D. Lauber, K. Engelke, and J. Weineck. Effects of single-vs. multiple-set resistance training on maximum strength and body composition in trained postmenopausal women. J. Strength Cond. Res. 18(4):000-000. 2004.-The purpose of this study was to examine the effect of a single-vs. a multiple-set resistance training protocol in well-trained early postmenopausal women. Subjects (N ϭ 71) were randomly assigned to begin either with 12 weeks of the single-set or 12 weeks of the multiple-set protocol. After another 5 weeks of regenerational resistance training, the subgroup performing the single-set protocol during the first 12 weeks crossed over to the 12-week multiple-set protocol and vice versa. Neither exercise type nor exercise intensity, degree of fatigue, rest periods, speed of movement, training sessions per week, compliance and attendance, or periodization strategy differed between exercise protocols. Body mass, body composition, and 1 repetition maximum (1RM) values for leg press, bench press, rowing, and leg adduction were measured at baseline and after each period. Multipleset training resulted in significant increases (3.5-5.5%) for all 4 strength measurements, whereas single-set training resulted in significant decreases (Ϫ1.1 to Ϫ2.0%). Body mass and body composition did not change during the study. The results show that, in pretrained subjects, multiple-set protocols are superior to single-set protocols in increasing maximum strength.

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“…The effects of acute exercise on testosterone stimulation have produced mixed results over the past few decades [67][68][69][70]. For example, a study investigating acute hormonal responses in elite junior Weightlifters found that the exercise protocol utilized caused a significant increase in serum testosterone, cortisol, GH, and whole blood lactate as compared to pre-exercise measures [68].…”

Section: Methods Of Increasing Testosterone Acute Exercisementioning

confidence: 99%

“…A recent study found that testosterone levels increased in both young (n=10) and middle-aged (n=8) men in response to acute, moderate intensity resistance exercise [67]. The results of another study indicated that serum testosterone levels were unchanged in men aged 55-70 years after a single bout of acute resistance exercise, despite an 18-fold increase in GH [70]. Linnamo et al, investigated the effects of maximal heavy resistance exercise on testosterone and GH levels in both men and women and found that GH increased in both genders while testosterone levels increased only in men following exercise [69].…”

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confidence: 98%

Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

Gunnels¹

2014

J Plant Biochem Physiol

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Low circulating testosterone levels can present numerous problems related to the overall health and well-being of individuals, men in particular. This finding is well-documented in the literature and low testosterone appears more prevalent in older men, in particular those who are physically inactive and who present with elevated levels of body fat. Multiple botanical (herbal) products have been claimed to elevate circulating testosterone in men; however, data pertaining to the use of such herbal preparations obtained from human clinical trials are limited. This review examines the research to date pertaining to the use of herbal ingredients with regards to their ability to elevate blood testosterone levels. A collective summary of the findings indicate that certain herbal supplements may actually yield an increase in testosterone (e.g., Longjack root), while most others have little to no evidence in support of their use in human subjects. Additional, well-controlled clinical trials are needed to generate data relative to the use of herbal dietary supplements to increase circulating testosterone. Testosterone is generally measured as either "free" (unbound) or "total" (unbound and chemically bound). Men who have a morning serum testosterone level < 300 ng/dL are considered to be "low" and may be a candidate for testosterone replacement therapy-which has become more common in recent years due to the increased diagnosis of andropause [55]. Insufficient levels of testosterone due to either impaired production or uptake can present serious health consequences due to the wide array of applications of testosterone within the human body. Areas including skeletal muscle health, muscular strength, and overall well-being/vitality seem to be significantly affected by testosterone status. Increasing Circulating Testosterone: Impact of Herbal Dietary SupplementsTrintThe role of testosterone in muscle growth has been investigated extensively in both humans and animals [56][57][58][59][60][61][62]. One study in men concluded that the testosterone-induced increase in muscle volume is due to muscle fiber hypertrophy [63]. A follow-up study conducted a year later noted muscle hypertrophy in men over a period of 20 weeks of treatment with a gonadotropin-releasing hormone agonist and a 125-, 300-, or 600-mg weekly dose of testosterone enanthate. The main findings from this study indicated that testosterone administration was associated with a significant increase in myonuclear number in men receiving the 300-and 600-mg doses.Muscular strength is another important factor that has been shown to be affected by testosterone levels in the body [56,61,62,[64][65][66]. A recent investigation utilized 267 men with stages 2-4 of Chronic Kidney Disease to assess the impact of testosterone level on a variety of variables [64]. This study found that testosterone was significantly and independently associated with handgrip strength, muscle mass, and nutritional status as the disease progressed. Another study explored short-term testoste...

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Testosterone, Growth Hormone and IGF-I Responses to Acute and Chronic Resistive Exercise in Men Aged 55-70 Years

Cited by 112 publications

References 11 publications

Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes

Exercise training-induced triglyceride lowering negatively correlates with DHEA levels in men with type 2 diabetes

Effects of Single- vs. Multiple-Set Resistance Training on Maximum Strength and Body Composition in Trained Postmenopausal Women

Increasing Circulating Testosterone: Impact of Herbal Dietary Supplements

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