Industry 4.0 this term originates from a project to promote computerization of manufacturing which was initiated by the German government, and the basic principle of industry 4.0 is the incorporation of machines, workflows, systems. The era of industrial revolution 4.0 is very influential in human life which is marked by rapid internet technology including the development of education. In the era of industrial revolution 4.0, there are many challenges faced in learning both for students and for teachers in vocational education, the content of practical teaching materials cannot enrich or adapt to the dynamics of society and the swift globalization. This is very important if it is associated with Citizenship Education which cannot be separated from the life that continues to grow, so in the midst of this global life, it is necessary to have better civic knowledge, civic skills, to face increasingly sophisticated lives. In this article, we argue that to improve citizenship competence in the industrial revolution 4.0 vocational education era is to develop 21st century based learning, digital literacy and technology become the main roles in this era balanced with human literacy and as the main foundation in carrying out this life is to believe to God.