“…In addition, MMPs maximize inflammation effect, by increased inflammatory cell recruitment, smooth muscle cell migration, atheroma swelling and, as a consequence, plaque instability [7,8]. The main MMPs that mediate atherosclerosis development are MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12 and MMP-13 [6,9]. The disintegrins and metalloproteinases proteins (ADAM-1, ADAM-8, ADAM-15), and MMPs tissue inhibitors (TIMP-1 and TIMP-2) [6] also participate in this intricate process.…”