Cardiovascular diseases represent the main cause of morbidity and mortality in the world and are epidemic events involving the atherosclerosis and coronary artery disease in particular. There are a wide variety of factors and markers associated with the development and aggravation of these diseases, including atherosclerosis. Subclinical Atherosclerosis can be determined by serum inflammatory markers present in the atherogenic process. Such markers can take a direct or indirect indicator role on atherosclerotic cardiovascular disease. The extracellular matrix metalloproteinases are biomarkers closely related into modifying and remodeling of vascular wall and other tissues and can represent predictive value patterns to support diagnosis. This review discusses the function and types of matrix metalloproteinases and its use as an indicator of support for the diagnosis of atherosclerosis.Keywords: ischemia; plaque, atherosclerotic; peptide hydrolases; atherosclerosis. RESUMOAs doenças cardiovasculares compreendem a maior prevalência de morbidade e mortalidade no mundo, sendo uma epidemia da qual se destacam a aterosclerose e a doença arterial coronária. Há grande diversidade de fatores e marcadores associados ao desenvolvimento e agravo dessas doenças, incluindo a aterosclerose, que subclinicamente pode ser evidenciada pela determinação de marcadores inflamatórios séricos participantes do processo aterogênico. Tais biomarcadores são considerados medidas diretas ou indiretas de doença cardiovascular aterosclerótica. As metaloproteinases estão relacionadas com a modificação/remodelamento da parede vascular e outros tecidos, podendo representar parâmetros com valor preditivo para o apoio diagnóstico. Esta revisão aborda o mecanismo de ação e os tipos de metaloproteinases de matriz, bem como seu uso como indicador de apoio

ABSTRACT. REClIARACTEKJZATION or TlfE SUIJGENUS

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The Systemic Arterial Hypertension (SAH) stands out among the chronic non-transmissible pathologies that impact the cause and/or aggravation of cardiovascular diseases (CVD) on a global level, as the disease is an underestimated disorder due to non-perceptive symptoms and associated with factors and risk markers of another CVD. Therefore, establishing the risk of progression and aggravation of the SAH, according the Framingham Risk Score (FRS), allows to reducing morbidity and improving preventative measures for DCVs. This observational and transversal study approaches the data collection of patient records at the Health Family Strategy of Senhor do Bonfim, BA, which established differences by descriptive and inferential statistical analysis (correlation and regression). The aspects of hypertension associated with risk factors for atherosclerosis were analyzed, determining the risk of developing cardiovascular events in 10 years by FRS. From 432 families, 746 patients were selected, of which 340 are hypertensive individuals (SAH = 45.57%) and 406 (NSAH = 54.42%) non-hypertensives. Among the SAH the majority (31.17%) was in the age range of 63 -77, but, in both groups, women were in stronger number. There was greater prevalence in SAH for all the characteristics analyzed, smoking (13.20%), sedentary (29.41%) and cardiovascular accident (22.60%). The SAH group is more susceptive to the CVD progress in 10 years by FRS (P < 0.0001 ANOVA). In the NSAH group, there were significant associations among all the variables analyzed as was expected, without differences between the linear correlation and regression, indicating the physio-metabolic equilibrium of the factors and markers evaluated by FRS. Already in SAH group, despite the correlations have been significant too, the regression analysis revealed that only Total Cholesterol (P = 0.0086); LDL (P < 0.0001), Glucose (P < 0.0006) and Age (P < 0.0001) have significative association with FRS. So, these factors and markers deserve more attention upon the health staff of Health Family Strategy, in the SAH course at studied population, attempt the highest cardiovascular risk by FRS (2.5 to 2.8 times) to SAH. The monitoring of high-risk patients should prioritize the lifestyle changes, employing preventive measures to SAH and CVD and atherosclerosis.

sobre a coleção malacológica "Eliseo Duarte" e apresenta uma revisão dos lo tes catalogados até o presente. A coleção foi adquirida pelo CNPq e encontra-se em custódia da Fundação Zoobotânica do Rio Grande do Sul. A classificação utilizada é a de TAYLOR & SOHL (1962) para a classe Gastropo• da, MOORE (1969) para a classe Bivalvia e RIOS (1985) para as Classes Polyplacophora, Scaphopoda e Cephalopoda. O ritmo de catalogação foi praticamente triplicado, devido ao alto grau de especialização atingido pelos bolsistas. Os lotes catalogados até agora são em número de 8.275 (um acréscimo de 4.561 lotes desde a última nota), com 47.239 exemplares. Isto corresponde a cerca de metade da coleção. O material provém de todo o mundo, achando-se distribuído pelas seguint"es regiões zoogeográficas: Holártica =3.277 lotes (39,6%); Neotropical =2.598 lotes (31,4%); Australiana =902 lotes (10,9%); Oriental = 662 lotes (8,0%); Etiópica = 447 lotes (5,4%); Antártica = 223 lotes (2,7%); Oceânica = 83 lotes (1 ,0%); sem pro