The anti‐emetic efficacy of maropitant (Cerenia™) in the treatment of ongoing emesis caused by a wide range of underlying clinical aetiologies in canine patients in Europe

Abstract

A single daily dose of maropitant was more effective than metoclopramide administered two or three times daily in the treatment of emesis caused by various aetiologies in dogs.

Efficacy of maropitant in preventing vomiting in dogs premedicated with hydromorphone

“…It has been shown to be highly effective in preventing vomiting secondary to a broad spectrum of emetic stimuli including cisplatin, apomorphine, copper sulfate, motion sickness and a wide range of clinical causes of vomiting (Benchaoui et al. 2007; De La Puente‐Rendondo et al. 2007a,b; Vail et al.…”

Efficacy of orally administered maropitant citrate in preventing vomiting associated with hydromorphone administration in dogs

“…[10][11][12][13][14] Underlying gastrointestinal tract dysfunction, along with upper airway abnormalities and surgical intervention, put dogs of brachycephalic breeds at increased risk of perianesthesia vomiting, regurgitation, aspiration pneumonia, and increased mortality rate. 21,22 It is also highly effective in preventing vomiting secondary to a broad spectrum of emetic stimuli, including cisplatin, apomorphine, copper sulfate, and motion sickness. [17][18][19][20] Maropitant is a neurokinin-1 receptor antagonist that has been approved to prevent and treat vomiting in dogs.…”

The use of maropitant to prevent vomiting induced by epidural administration of preservative free morphine through an epidural catheter in a dog

“…Pre‐administration of maropitant citrate, a highly specific neurokinin NK1 receptor antagonist (de la Puente‐Redondo et al. 2007) appeared to prevent vomiting in our patient after the injection of epidural morphine.…”