The Antioxidant properties of para-Aminobenzoic acid and its sodium salt

Selective Oxidation of 2-Hydroxypropyl Ethers of Cellulose and Dextran: Simple and Efficient Introduction of Versatile Ketone Groups to Polysaccharides

“…We selected p-aminobenzoic acid (pABA) as a suitable primary amine for the preparation of a model drug conjugate with Ox-HPC. It was employed primarily to represent structures in amine-containing aromatic drugs and other bioactives, but pABA is also a known precursor to folic acid with therapeutic uses as an antioxidant, 51 antibacterial, 52 and antimutagenic 53 agent. In the event, the reaction of pABA with Ox-HPC in methanol indeed provided the target imine.…”

Metabolomics Combined with Correlation Analysis Revealed the Differences in Antioxidant Activities of Lotus Seeds with Varied Cultivars

“…Nuciferine was reported to protect against obesity-induced nephrotoxicity through its hypolipidemic, anti-inflammatory, and antioxidant effects [52]. In addition, p-aminobenzoic acid, uridine, and indole-3-carbinol were reported to possess significant antioxidant activities [45,53,54]. It was found that the relative content of these three metabolites was significantly higher in TK66 than in the other cultivars (Figure 3a), which might contribute to the higher antioxidant activities of TK66.…”

“…Nuciferine was reported to protect against obesity-induced nephrotoxicity through its hypolipidemic, anti-inflammatory, and antioxidant effects [52]. In addition, p-aminobenzoic acid, uridine, and indole-3-carbinol were reported to possess significant antioxidant activities [45,53,54]. It was found that the relative content of these three metabolites was significantly higher in TK66 than in the other cultivars (Figure 3a), which might contribute to the higher antioxidant activities of To clarify the metabolites that were highly correlated with the antioxidant activities in LS, metabolites with |r| > 0.5 and p < 0.05 were further screened, and a correlation network among metabolites and antioxidant activities was established (Figure 5b).…”

Crystal structure of a 1:1 salt of 4-aminobenzoic acid (vitamin B10) with pyrazinoic acid

“…4-Aminobenzoic acid (PABA) is known as vitamin B 10 and is involved in the production of folic acid in bacteria (Chang & Hu, 1996;Akberova, 2002). It is used as an antibacterial (Richards et al, 1995), anti-inflammatory (Flindt-Hansen & Ebbesen, 1991), antioxidant (Sirota et al, 2017;Galbinur et al, 2009), anticoagulant (Stroeva et al, 1999;Drozd et al, 2000), or dermatologic agent (Rothman & Henningsen, 1947;Xavier et al, 2006;Hanson et al, 2006). Moreover, it is a building block used in the design of drug candidates and is frequently found as a structural moiety in drugs (Kluczyk et al, 2002).…”