The Association of Functional Capacity With Right Atrial Deformation in Patients With Pulmonary Arterial Hypertension: A Study With Two-Dimensional Speckle Tracking

Liu, Weiwei; Wang, Yueheng; Zhou, Jinling; Bai, Hui; Wang, Feng; Wang, Ju

doi:10.1016/j.hlc.2017.02.029

Cited by 17 publications

(20 citation statements)

References 28 publications

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“…The study compared patients with healthy subjects, which had a right atrial strain similar to the values described in the literature, with a mean deformation of 44%. 8,9 The group of pulmonary hypertension underwent modifications in all stages of the atrial cycle predominating in the reservoir phase, very similar to that compared with the literature. 3,8,9 Limitations of our study also included a reduced sample size, interoperator variability in estimating the pulmonary pressure, heterogeneity in etiology across patients with pulmonary hypertension, differences in population regarding sex, age and severity of the disease.…”

Section: Discussionsupporting

confidence: 66%

“…8 There is clinical correlation between worse functional capacity and atrial strain in patients with pulmonary hypertension, mainly driven by variations in the www.medigraphic.org.mx reservoir phase. 9 The role of right atrial strain as a predictor of hemodynamic parameters has also been described in patients with pulmonary hypertension with a significant correlation with the cardiac index, functional class and BNP, demonstrating that atrial function is affected prior to structural changes. 10 The evaluation of atrial function through 2D echocardiography is a very useful tool due to the clinical implications that lead to atrial dysfunction.…”

Section: Figurementioning

confidence: 94%

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Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Sánchez-Hernández¹,

Martin²,

Larraya-Indaberea³

et al. 2019

CIU Cardiac Image Updated

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Atrial and ventricular function are closely related. Right atrial strain is currently being studied for validation. The purpose of our research is to evaluate its behavior in patients with pulmonary hypertension and compare it with healthy adults, with the hypothesis that right atrial strain would be lower in the first group. Methods: This is an observational, cross-sectional study. Only subjects with secondary pulmonary hypertension were included in the patient group. Subjects underwent systematic echocardiography with equipment from Philips (Epic 7), acquiring routine 2D images in standard and modified 4 chamber view, for assessment of right atrial function and estimated pulmonary arterial systolic pressure in both groups. The respective post-processing analysis software used was QLAB 9 (Cardiac motion quantification (CMQ)). Results: A total of 60 subjects, 30 in each group, were included. The mean age was 78 years in the pulmonary hypertension group (60% male), and 26 years in the healthy subjects (16% males). The mean pulmonary systolic pressure in the patient group was 60 mmHg (p <0.0001). Right atrial mean global longitudinal strain was 17.8% in patient group vs 44% in the control group, p <0.0001. Conclusions: The longitudinal global strain of the right atrium is significantly lower in patients with pulmonary hypertension compared against healthy subjects. The reservoir phase of the atrial cycle had the biggest difference in deformation between both groups.

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Section: Discussionsupporting

confidence: 66%

Section: Figurementioning

confidence: 94%

Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Sánchez-Hernández¹,

Martin²,

Larraya-Indaberea³

et al. 2019

CIU Cardiac Image Updated

View full text Add to dashboard Cite

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“…Based on these previous results, STE is now increasingly used in human clinical trials to unmask and follow-up subtle alterations in LV function [ 27 ]. Moreover, STE is also capable to assess right ventricular and also atrial deformation, which measurements will contribute to a more complex understanding of diabetic cardiomyopathy [ 28 , 29 ].…”

Section: Discussionmentioning

confidence: 99%

Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

Mátyás

Kovács

Németh

et al. 2018

Cardiovasc Diabetol

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BackgroundMeasurement of systolic and diastolic function in animal models is challenging by conventional non-invasive methods. Therefore, we aimed at comparing speckle-tracking echocardiography (STE)-derived parameters to the indices of left ventricular (LV) pressure–volume (PV) analysis to detect cardiac dysfunction in rat models of type-1 (T1DM) and type-2 (T2DM) diabetes mellitus.MethodsRat models of T1DM (induced by 60 mg/kg streptozotocin, n = 8) and T2DM (32-week-old Zucker Diabetic Fatty rats, n = 7) and corresponding control animals (n = 5 and n = 8, respectively) were compared. Echocardiography and LV PV analysis were performed. LV short-axis recordings were used for STE analysis. Global circumferential strain, peak strain rate values in systole (SrS), isovolumic relaxation (SrIVR) and early diastole (SrE) were measured. LV contractility, active relaxation and stiffness were measured by PV analysis.ResultsIn T1DM, contractility and active relaxation were deteriorated to a greater extent compared to T2DM. In contrast, diastolic stiffness was impaired in T2DM. Correspondingly, STE described more severe systolic dysfunction in T1DM. Among diastolic STE parameters, SrIVR was more decreased in T1DM, however, SrE was more reduced in T2DM. In T1DM, SrS correlated with contractility, SrIVR with active relaxation, while in T2DM SrE was related to cardiac stiffness, cardiomyocyte diameter and fibrosis.ConclusionsStrain and strain rate parameters can be valuable and feasible measures to describe the dynamic changes in contractility, active relaxation and LV stiffness in animal models of T1DM and T2DM. STE corresponds to PV analysis and also correlates with markers of histological myocardial remodeling.Electronic supplementary materialThe online version of this article (10.1186/s12933-017-0645-0) contains supplementary material, which is available to authorized users.

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“…Previous research has highlighted the prognostic and clinical values of the LA and RA functions as evaluated with 2D speckle‐tracking echocardiography in some conditions . Two‐dimensional speckle‐tracking echocardiography is an assessment method for atrial functions and can detect atrial dysfunction, however subtle …”

Section: Discussionmentioning

confidence: 99%

“…Previous research has highlighted the prognostic and clinical values of the LA and RA functions as evaluated with 2D speckle-tracking echocardiography in some conditions. [21][22][23][24] Two-dimensional speckle-tracking echocardiography is an assessment method for atrial functions 11,12 and can detect atrial dysfunction, however subtle. 25,26 To our knowledge, our study is the first of its kind to compare the RA and LA functions as assessed with 2D speckle-tracking echocardiography both between patients having undergone device and surgical ASD closure 1 to 5 years previously and between them and a healthy control group.…”

Section: Discussionmentioning

confidence: 99%

Assessment of the Right and Left Atrial Functions at Midterm After Surgical and Device Atrial Septal Defect Closure: A 2‐Dimensional Speckle‐Tracking Echocardiographic Study

Haji-Zeinali

Iri

Hosseinsabet

2018

J of Ultrasound Medicine

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Objectives The available literature lacks data on the comparison of the functions of the right atrium (RA) and left atrium (LA) between surgical atrial septal defect (ASD) closure and percutaneous device ASD closure at follow‐up durations of longer than 1 year. We sought to evaluate the RA and LA functions in patients who underwent surgical or device ASD closure between 1 and 5 years postprocedurally. Methods The study population included 30 patients who underwent device ASD closure and 30 who underwent surgical ASD closure, who were matched for the procedural time, age, and sex, in addition to 30 control participants. The RA and LA functions were evaluated with 2‐dimensional speckle‐tracking echocardiography. Results The LA systolic and early diastolic strain and strain rate values and the RA early diastolic strain rate in the device closure group were more likely to be abnormal than in the control group. The RA systolic and late diastolic strain and strain rate values, the RA early diastolic strain rate, and the LA early diastolic strain in the surgical closure group were more likely to be abnormal than in the control group. The RA systolic strain and strain rate in the surgical closure group were more likely to be abnormal than in the device closure group. Conclusions The LA reservoir and conduit functions and the RA contraction function in the patients who underwent device ASD closure and all of the RA functions and the LA conduit function in the patients who underwent surgical ASD closure were more likely to be abnormal than those in the control participants. The RA reservoir function in the surgical closure group was more likely to be abnormal than that in the device closure group.

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The Association of Functional Capacity With Right Atrial Deformation in Patients With Pulmonary Arterial Hypertension: A Study With Two-Dimensional Speckle Tracking

Cited by 17 publications

References 28 publications

Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Comparación del strain longitudinal de auricular derecha en hipertensión pulmonar y sujetos normales

Comparison of speckle-tracking echocardiography with invasive hemodynamics for the detection of characteristic cardiac dysfunction in type-1 and type-2 diabetic rat models

Assessment of the Right and Left Atrial Functions at Midterm After Surgical and Device Atrial Septal Defect Closure: A 2‐Dimensional Speckle‐Tracking Echocardiographic Study

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