The article discusses the state influence on the development of digital economy of rational nature use in the agro-sector of the region's economy. The indicated sector of the region's economy demonstrates a mismatch between the tasks of the agroindustrial complex restructuring and the current market conditions oriented towards the widespread use of the digital economy elements, introduction of technological innovations and modernization of agricultural production. The modern way trends of the socio-economic system development dictate the need to use a development model that does not cause harm to nature or minimizes it. Realization of this statement can be ensured with a harmonious combination of environmental, innovative and economic components aimed at a balanced nature management. The authors assert that digital transformation of the agricultural sector should be considered as the basis of food security and the maximum production intensification. The key state program aimed at a direct impact implementation on environmental management in the agricultural sector of the region's economy through the digital economy has been analyzed. The conclusion is drawn on the application of this program at the regional level, as well as on a particular example of the experience of the state introducing modern management methods which have a synergistic effect for the real sector of the regional economy. The article presents some particular recommendations that should be paid attention while implementing the elements of the digital economy on the processes of environmental management in the agricultural sector of the region's economy.