The Biological Effects of Sumilarv and Flubex on Dengue Fever Vector Aedes aegypti in Jeddah Governorate Saudi Arabia

Al-Azab, Abbas M.; AlGhamdi, Khalid M.; Shaheen, Mohamed; Zaituon, Ahmed A.

doi:10.13005/bbra/1115

Cited by 7 publications

(4 citation statements)

References 10 publications

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“…However, our study, which utilized spatial analysis to assess the efficacy of AD-PPF by determining the clustering of dengue incidence, is new. Previous studies on AD-PPF only involved the evaluation of the efficacy of PPF granules [ 34 , 59 , 60 ] or the assessment of Aedes mosquitoes’ resistance to PPF [ 61 , 62 , 63 ], but not on the use of spatial analysis to identify the clustering of DENV infection after being exposed to AD-PPF.…”

Section: Discussionmentioning

confidence: 99%

Efficacy Assessment of Autodissemination Using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Parañaque City, Philippines: A Spatial Analysis

et al. 2023

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Dengue is one of the most important vector-borne diseases worldwide and is a significant public health problem in the tropics. Mosquito control continues to be the primary approach to reducing the disease burden and spread of dengue virus (DENV). Aside from the traditional larviciding and adulticiding interventions, autodissemination using pyriproxyfen-treated (AD-PPF) ovitraps is one of the promising methods to complement existing vector control strategies. Our paper assessed the efficacy of AD-PPF in reducing DENV infections in two barangays in Parañaque City. Using saliva samples from the participants from both the control and intervention sites, we collected the seroprevalence data for three months in each of the two years. Spatial analysis was conducted to determine hotspot areas and identify DENV infection distributions across the trial periods. The results showed that the intervention site was identified as having a clustering of DENV infections in Month 0 of Year 1 and shifted to a random dispersion of dengue cases at the end of Month 3 in Year 2. The disappearance of the clustering of the intervention site translates to a decrease in the cases of DENV infection relative to the control site. Furthermore, we also identified that DENV transmission occurred at a small-scale level that did not go beyond 86 m. In conclusion, AD-PPF is suggested to be an effective strategy and may be used as an additional vector control approach, albeit based on this short-term implementation.

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Section: Discussionmentioning

confidence: 99%

Efficacy Assessment of Autodissemination Using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Parañaque City, Philippines: A Spatial Analysis

et al. 2023

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“…However, our study, which utilized spatial analysis to assess the efficacy of AD-PPF by determining the clustering of dengue incidence, is new. Previous studies on AD-PPF only involved the evaluation of the efficacy of PPF granules [52][53][54] or the assessment of Aedes mosquitoes' resistance to PPF [55][56][57], but not on the use of spatial analysis to identify clustering of DENV infection after being exposed to AD-PPF.…”

Section: Discussionmentioning

confidence: 99%

Efficacy Assessment of Autodissemination using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Two Barangays in Parañaque City, Philippines: A Spatial Analysis

Ligsay¹,

Regencia²,

Tambio³

et al. 2022

Preprint

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Dengue infection is one of the most important vector-borne diseases worldwide and is a significant public health problem in the tropics. Mosquito control continues to be the primary approach to reducing the disease burden and the dengue virus (DENV) spread. Aside from the traditional larviciding and adulticiding interventions, autodissemination using pyriproxyfen-treated (AD-PPF) ovitraps is one of the promising methods to complement existing vector control strategies. Our paper assessed the efficacy of AD-PPF in reducing DENV infection in two barangays in Parañaque City. Using saliva samples from the participants from both the control and intervention sites, we collected the seroprevalence data for three months in each of the two years. Spatial analysis was conducted to determine hotspot areas and identify DENV infection distributions across the trial periods. Results showed that the intervention site was identified as having clustering of DENV infection in Month 0 of Year 1 and shifted to random dispersion of dengue cases at the end of Month 3 in Year 2. The disappearance of the clustering of the intervention site translates to a decrease in the cases of DENV infection relative to the control site. Furthermore, we also identified that DENV infection transmission occurs at a small-scale level that did not go beyond 86 meters. In conclusion, AD-PPF is suggested to be an effective strategy and may be used as an additional vector control approach, albeit in its short-term implementation.

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“…There are references about the inhibitory concentration of DFB due to its effect on adult emergence, especially in works where larval mortality has been low, for example, that obtained from 10 and 38% by Al‐Azab, Al‐ghamdi, Shaheen, and Zaituon () with concentrations between 0.0004 and 0.008 ppm, and lower mortality from 2% to 20% with the same concentrations by Al‐Azab and Shaalan (), whereas Kamal and Khater () observed a higher mortality of 24% with 0.003 ppm.…”

Section: Discussionmentioning

confidence: 99%

“…Mosquitos are responsible for the transmission of several pathogens of medical importance, such as viruses, bacteria, and nematodes, which cause severe diseases that each year cause the death of about a million people around the world (American Mosquito Control Association, ; Becker et al, ). In particular, the hematophagous mosquito Aedes aegypti is the main vector of chikungunya and of pandemics of flaviviruses, such as dengue, zika, yellow fever, and other viral diseases, the habitat of which is closely related to the conditions inside and outside the houses where human populations are established (Beserra, de Freitas, de Souza, Fernandes, & Santos, ; Evans, Elliot, & Barreto, ; Santos, Teixeira, Alberti, Furtado, & Rodrigues, ; World Health Organization, ).…”

Section: Introductionmentioning

confidence: 99%

Susceptibility and alterations by diflubenzuron in larvae of Aedes aegypti

Montaño‐Reyes

Llanderal-Cázares

Váldez-Carrasco

et al. 2019

Arch Insect Biochem Physiol

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Benzoylphenyl ureas inhibit chitin synthesis and interfere with the molting process in arthropods. In this study, the effect of diflubenzuron on third‐instar larvae of Aedes aegypti was evaluated. The susceptibility to the product was determined, and the alterations generated were shown through light and electron microscopy. LC50 and LC90 were 0.23 and 0.47 ppm, respectively. The main alterations observed were the incapacity to complete the molt, a reduction of mobility, the fragmentation of the old cuticle, a division of the body segments that was not evident, and the deformation of the caudal structures. Images of the ultrastructure are included, where breaking zones in the cuticle were observed, separation of the cuticle, the epidermis and the muscles, and these latter with a disorganized arrangement. In low concentrations, from 0.15 ppm, diflubenzuron causes alterations in the behavior and morphology of Ae. aegypti.

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The Biological Effects of Sumilarv and Flubex on Dengue Fever Vector Aedes aegypti in Jeddah Governorate Saudi Arabia

Cited by 7 publications

References 10 publications

Efficacy Assessment of Autodissemination Using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Parañaque City, Philippines: A Spatial Analysis

Efficacy Assessment of Autodissemination Using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Parañaque City, Philippines: A Spatial Analysis

Efficacy Assessment of Autodissemination using Pyriproxyfen-Treated Ovitraps in the Reduction of Dengue Incidence in Two Barangays in Parañaque City, Philippines: A Spatial Analysis

Susceptibility and alterations by diflubenzuron in larvae of Aedes aegypti

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