The biological properties of lactоbacilli strains isolаted from food of plant origin and edible plants

Abstract

Вивчено біологічні властивості лактобактерій, ізольованих із етнічних страв і їстівних рослин країн регіону Чорного моря. Дані штами характеризуються специфічними антагоністичними властивостями та здатністю модулювати локальну імунну відповідь організму, тому вони можуть використовуватись як закваски у виготовленні новітніх ферментованих харчових продуктів із заданими властивостями і як компоненти про-чи синбіотичних біопрепаратів Ключові слова: лактобактерії, етнічні ферментовані продукти харчування, антагоністична активність, чутливість до антибіотиків, імуномодуляторний вплив The biological properties of Lactobacilli, isolated from ethnical foods and edible plants of the Black Sea region' countries had been studied. These strains characterized by specific antagonistic properties and the ability to modulate host local immune response. Thus these strains could be used as microbial starters in the production of newly designed fermented foods of plant origin with predicted properties or as basic components of pro-or

Novel functional food for prevention of non-communicable diseases

“…Based on the results of our previous studies [3,15], we have proposed the principles of creating a new generation FFP based on plant components and microorganisms for the purpose of their prognostic and personified application for preventing the emergence of noncommunicable diseases [6], through correction of microbial cenosis in the intestines of the macroorganism .…”

“…It was determined by the method of delayed antagonism and agar blocks behind Yegorov [3]. In addition, these strains of lactobacilli are characterized by specific immunomodulatory properties studied earlier in experiments on mice of the BALB / C line [3] and synergistic properties [6]. In similar studies, we have shown the ability of probiotic microorganisms to stimulate the local immune response and mechanisms that provide it [15,19].…”

“…Previously, their high and selective antagonistic activity with respect to a number of opportunistic bacteria (namely, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli enteropathogenic (EPEC), Enterobacter cloacae, Morganella morganii, Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), Staphylococcus hominis, Proteus mirabilis, Salmonella enterica subsp. enterica serovar Enteritidis, Shigella flexneri) has been demonstrated [3]. It was determined by the method of delayed antagonism and agar blocks behind Yegorov [3].…”

“…enterica serovar Enteritidis, Shigella flexneri) has been demonstrated [3]. It was determined by the method of delayed antagonism and agar blocks behind Yegorov [3]. In addition, these strains of lactobacilli are characterized by specific immunomodulatory properties studied earlier in experiments on mice of the BALB / C line [3] and synergistic properties [6].…”

“…We have developed and proposed for production of FFP with the expected (prognostic, predefined) specific properties. This is a sour milk drink consisting of pre-selected with biological properties established in vitro and in vivo [3,4] the probio tic composition of authors strains of microorganisms Lactobacillus casei ATCC 27139, Lactobacillus plantarum JCM 1149, L. casei MGB63-1, L. plantarum and prebiotic component presented by extracts (freshly dried juice) of сherry plum, blueberries, pomegranate, persimmon and сornelian cherry. These plant extracts (berries) are rich in biologically active substances (BAS) and are characterized by the ability to modulate the microbiocenosis of human intestine causing its correction towards a reduction of pathogenic and opportunistic pathogens and growth of beneficial microorganisms, antioxidant and antiinflammatory properties [13,26].…”