Driven by continuing scaling of Moore's law, chip multiprocessors and systems-on-a-chip are expected to grow the core count from dozens today to hundreds in the near future. Scalability of on-chip interconnect topologies is critical to meeting these demands. In this work, we seek to develop a better understanding of how network topologies scale with regard to cost, performance, and energy considering the advantages and limitations afforded on a die. Our contributions are three-fold. First, we propose a new topology, called Multidrop Express Channels (MECS), that uses a one-to-many communication model enabling a high degree of connectivity in a bandwidth-efficient manner. In a 64-terminal network, MECS enjoys a 9% latency advantage over other topologies at low network loads, which extends to over 20% in a 256-terminal network. Second, we demonstrate that partitioning the available wires among multiple networks and channels enables new opportunities for trading-off performance, area, and energy-efficiency that depend on the partitioning scheme. Third, we introduce Generalized Express Cubes -a framework for expressing the space of on-chip interconnects -and demonstrate how existing and proposed topologies can be mapped to it.