The Carcinogenic Liver Fluke Opisthorchis viverrini among Rural Community People in Northeast Thailand: a Cross-Sectional Descriptive Study using Multistage Sampling Technique

Kaewpitoon, Soraya J; Kaewpitoon, Natthawut; Rujirakul, Ratana; Ueng-arporn, Naporn; Matrakool, Likit; Tongtawee, Taweesak

doi:10.7314/apjcp.2015.16.17.7803

Cited by 8 publications

(4 citation statements)

References 14 publications

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“…This decreased to 6.3% in the third year of the study. In those with first time liver fluke infections, with treatment and health education, the participants came to understand the severity of opisthorchiasis as well as of cholangiocarcinoma [22]. However, their lifestyles led them to become reinfected due to their cultural behaviors [23].…”

Section: Discussionmentioning

confidence: 99%

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Reduction of Reinfection Rates with Opisthorchis viverrini through a Three-Year Management Program in Endemic Areas of Northeastern Thailand

Prakobwong

Suwannatrai

2020

Korean J Parasitol

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To clarify the reinfection profile associated with risk factors of opisthorchiasis, we conducted an epidemiological study on the chemotherapeutic effects on reinfection with O. viverrini in the endemic areas of Northeastern Thailand for 3 years. A total of 3,674 fecal samples were collected from participants in villages of 5 provinces. They were examined microscopically using a modified technique of formalin ethyl-acetate concentration. Egg-positive residents were reexamined year (2018) by year (2019) after treatment with a single dose (40 mg/kg) of praziquantel. Health education was provided to the participants yearly. The egg-positive rate of O. viverrini was 14.3%, and was highest (22.2%) in the 20-30 year-old group in 2017. The egg positive rate was 15.3% in dogs and 11.4% cats. Human reinfection rate was 15.5% and 6.3% in next 2 years, and was highest (23.2%) among the fishermen. Relative risk factors of reinfection were significantly higher for males, over 40-year-old age, or working as fishermen or farmers, and eating uncooked fish within the preceding year. A significant difference resulting from a health education program was observed in the third year. Therefore, health education and sustainable surveillance for opisthorchiasis should be maintained to decrease the risk of reinfection.

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Section: Discussionmentioning

confidence: 99%

“…These groups did not receive health education as infected participants, and may have become reinfected. In this case, the severity of opisthorchiasis may have been underestimated [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

Reduction of Reinfection Rates with Opisthorchis viverrini through a Three-Year Management Program in Endemic Areas of Northeastern Thailand

Prakobwong

Suwannatrai

2020

Korean J Parasitol

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“…Additionally, infection rate was higher among males (27.6%) than among women (21.4%) 16 . In 2010 and 2015, the results of surveillance that included 17 community-based surveys demonstrated a high prevalence of > 20%, and the highest prevalence (45.7%) was observed in a community in the northeastern region 17 . In 2023, the prevalence of O. viverrini in Chaiyaphum Province, northeastern Thailand, was 7.15%, which was higher than that in the national surveillance conducted in 2019, which reported a prevalence of only 2.2% 18 .…”

Section: Moreover Based On Fecal Screening For O Viverrini Infection ...mentioning

confidence: 99%

“…In 2023, the prevalence of O. viverrini in Chaiyaphum Province, northeastern Thailand, was 7.15%, which was higher than that in the national surveillance conducted in 2019, which reported a prevalence of only 2.2% 18 . Despite a decline in the overall prevalence at the national level, many studies have indicated that the infection rate of O. viverrini remains high in several communities within the northeastern areas [17][18] .…”

Section: Moreover Based On Fecal Screening For O Viverrini Infection ...mentioning

confidence: 99%

The Past and Present Situation of Opisthorchis viverrini Infection in Thailand

Buathong,

Charoensuk,

Suwannahitatorn

2024

Vajira Med J

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Opisthorchis viverrini, a major foodborne trematode, remains a major public health concern in Thailand, particularly in the northern and northeastern provinces. O. viverrini can be transferred to people and reservoir hosts through the consumption of uncooked cyprinid fish with metacercariae. Chronic infection with O. viverrini can lead to a severe condition known as cholangiocarcinoma (CCA). According to the Nationwide Hospital Admission Database, Thailand has experienced the highest incidence of CCA globally in recent years. Particularly, between 2009 and 2013, there was an incidence rate of 14.6 cases per 100,000 individuals within the population and a corresponding mortality rate (MR) of 14%. In addition, high incidence rates of CCA were reported in Khon Kaen Province from 1989 to 2018, with a rate of 36.1 per 100,000 person-years in men and 14.4 per 100,000 person-years in women. Despite the reduction in the overall prevalence of O. viverrini at the national level, several studies have indicated that the infection remains highly prevalent in some communities in the northeastern and northern regions. Some communities have demonstrated a prevalence of O. viverrini exceeding 20%, and rates reaching as high as 45.7%. Therefore, in populations with a high prevalence, programs to control this parasite should be implemented, including monitoring eating habits. This review article provides a comprehensive overview of the current distribution of O. viverrini in Thailand, outlining its pathophysiology, background, and preventive and control strategies. In addition, this review suggests that individuals in high-risk communities should act to eradicate liver fluke, as this is crucial for the overall health of the community.

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Changing patterns of prevalence in Opisthorchis viverrini sensu lato infection in children and adolescents in northeast Thailand

et al. 2016

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The Carcinogenic Liver Fluke Opisthorchis viverrini among Rural Community People in Northeast Thailand: a Cross-Sectional Descriptive Study using Multistage Sampling Technique

Cited by 8 publications

References 14 publications

Reduction of Reinfection Rates with Opisthorchis viverrini through a Three-Year Management Program in Endemic Areas of Northeastern Thailand

Reduction of Reinfection Rates with Opisthorchis viverrini through a Three-Year Management Program in Endemic Areas of Northeastern Thailand

The Past and Present Situation of Opisthorchis viverrini Infection in Thailand

Changing patterns of prevalence in Opisthorchis viverrini sensu lato infection in children and adolescents in northeast Thailand

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