The Coexistence of Coeliac Disease, Psoriasis and Vitiligo

Abstract

ÖzetÇölyak hastal›¤›n›n psoriasis ve vitiligo da dahil olmak üzere ço¤u otoimmun kökenli olan baz› hastal›klarla birlikteli¤i tan›mlan-m›flt›r. Burada palmoplantar pustular psoriasis tan›s› konulan ve özgeçmiflinde çölyak ve vitiligo hastal›¤› bulunan 26 yafl›nda bir kad›n olgu bildirilmektedir. Vitiligo, psoriasis ve çölyak hastal›¤› s›k görülen hastal›klar olup literatürde çölyak hastal›¤› ile birlikte olan vitiligo ya da psoriasis olgular› bildirilmifl olsa da, üçünün bir arada oldu¤u bir olguya rastlanmam›flt›r. Her ne kadar psoriasis ve vitiligo lezyonlar›n›n çölyak hastal›¤› ile birlikteli¤inin rastlant›sal olma olas›l›¤› bulunmakla beraber, bu olgu özellikle otoimmun kö-kenli ve kronik seyirli dermatozlarda çölyak hastal›¤› olas›l›¤›n›n da akla getirilmesi ve buna yönelik sorgulama yap›lmas›n›n öne-mini vurgulamak amac›yla sunulmaktad›r. (Türkderm 2010; 44: 102-4 SummaryIt has been defined that coeliac disease is associated with most of the autoimmune diseases including psoriasis and vitiligo. Here, a 26-year-old woman who was diagnosed palmoplantar pustular psoriasis and already had coeliac disease and vitiligo is reported. According to our opinions, this is the first report describing the development of these three disorders in one patient, even though vitiligo, psoriasis and coeliac disease are common disorders, and the coexistence of the two of them has been previously reported in the literature. This case has been presented to emphasize the importance of considering and inquiring the possible coeliac disease in chronic and autoimmune dermatoses, although psoriasis and vitiligo may have coincidental associations with coeliac disease. (Turkderm 2010; 44: 102-4)

Evaluation of audiovestibular system in psoriasis patients without joint involvement

“…However, the autoimmune mechanism characterized by T cell‐mediated hyperproliferation of keratinocytes has been implicated in the etiology. It has been reported that psoriasis may be associated with other autoimmune diseases 1 . Although psoriasis has been described as a skin disease, it is associated with many comorbidities.…”