During decolonization, Henri Collomb was appointed to the first Chair of Psychiatry at the University of Dakar. Using a neuropsychiatric approach, he quickly made significant advances in the field, despite the colonial era's poor legacy of assistance facilities for mentally ill people. Through alliances with professors and researchers from the university Departments of Psychology and Sociology, an original interdisciplinary dialogue was set up to build up a research team which would develop rich and varied activities in the fields of transcultural psychiatry, medical anthropology and psychoanalytic anthropology. The methodological and theoretical contributions of such an approach are well illustrated in the book Œdipe africain by M-C and E Ortigues and in the journal founded in 1965, Psychopathologie africaine.