The crystal structure of 1,5-dibenzyl-1H-pyrazolo[3,4-d]pyrimidine-4(5H)-thione

Abstract

In the title compound, C19H16N4S, the pyrazolo­[3,4-d]pyrimidine ring is close to being planar, with the greatest deviation from the mean plane being 0.023 (2) Å for the C atom bearing the thione S atom. The two phenyl rings are nearly perpendicular to the fused ring system [dihedral angles = 71.4 (2) and 78.1 (2)°], but are oriented in opposite directions; the dihedral angle between the phenyl rings is 32.22 (16)°. In the crystal, linear supra­molecular chains along [101] are sustained by C—H⋯S inter­actions.

Crystal structure of 1,5-diethyl-3′,5′-diphenyl-1,5-dihydro-3′H-spiro[pyrazolo[3,4-d]pyrimidine-4,2′-[1,3,4]thiadiazole]

“…antagonists (Taliani et al, 2010 and as antitubercular agents (Trivedi et al, 2012 (El Fal et al, 2014;El Fal et al, 2015;Ahoya et al, 2011, Anothane et al, 2012.…”

Synthesis, and evaluation of α-amylase and α-glucosidase inhibitory potential of new pyrazolo[3,4-d]pyrimidine derivatives

“…In continuation of our work on the synthesis of the excess of allopurinol [16][17][18][19][20][21][22][23], we have envisioned the synthesis new pyrazolo [3,4-b]pyridine derivatives by thionation, alkylation and 1,3-dipolar cycloaddition reactions in order to evaluate their inhibitory effect of α-amylase and α-glucosidase. The melting points were taken on an electrothermal capillary melting point apparatus.…”