The CSF Diversion via Lumbar Drainage to Treat Dialysis Disequilibrium Syndrome in the Critically Ill Neurological Patient

Clinical Analysis of Lumbar Pool Drainage Combined with Antibiotics in the Treatment of Intracranial Infection

“…Lumbar puncture can measure intracranial pressure and collect cerebrospinal fluid for culture and biochemical indexes, and continuous drainage of the lumbar pool can also measure intracranial pressure and collect cerebrospinal fluid for culture and biochemical indexes [12]. However, the success rate of bacterial culture of cerebrospinal fluid in intracranial infections in clinical practice is low, requiring repeated and multiple cultures and biochemical indicators [13]; continuous lumbar pool drainage has significant advantages in the treatment of intracranial infections, such as the advantages of requiring only a single lumbar puncture, high success rate, controlled drainage rate, avoidance of associated adverse effects, easy detection of drained cerebrospinal fluid, and large cumulative drainage volume [14].…”

Uremic encephalopathy

“…In refractory cases, lumbar drain and invasive CSF diversion to reduce intracranial pressure have been successfully performed. 140 Lack of improvement in cognitive dysfunction with dialysis may also reflect suboptimal and discontinuous treatment regimens that impair meeting clearance goals. As there is little evidence that the achievement of target Kt/V is sufficient to correct or prevent uremic encephalopathy, in case of suboptimal CNS improvement, higher clearance targets may be required and should be considered.…”

Dialysis Disequilibrium Syndrome Induced Seizure Following Hemodialysis

“…Neurological symptoms and signs during or shortly following dialysis are known as DDS. Seizure after hemodialysis is associated with the osmotic fluid shift due to the alteration of urea level [ 4 , 5 ]. Although the prevalence of seizures in hemodialysis was quite common, the prevalence of seizures due to DDS was quite rare [ 6 ].…”