The Dasyscyphins A—C and Niveulone, New Biologically Active Compounds from the Ascomycete Dasyscyphus niveus.

Abstract

Terpenes U 0200The Dasyscyphins A-C and Niveulone, New Biologically Active Compounds from the Ascomycete Dasyscyphus niveus. -Whereas dasyscyphin A (I) does not exhibit significant biological activity, dasyscyphins B (II) and C (III) show cytotoxic activity against human HepG2, Hela S3, U937, Colo-320 and Jurkat cell lines with IC50 of 0.5 ≈ 3 ug/ml. The activity of niveulone (IV) is less pronounced. -(MIERAU, V.; ROJAS DE LA PARRA, V.; STERNER, O.; ANKE*, T.; J.