1989
DOI: 10.1176/ajp.146.4.503
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The DST in children and adolescents with major depressive disorder

Abstract: The authors analyzed dexamethasone suppression test (DST) results from 13 prospective studies on the use of the DST in children and adolescents with psychiatric disorders. Sensitivity of the DST was significantly higher among the children than among the adolescents with major depressive disorder (69.6% and 47.1%, respectively), and specificity was significantly lower (69.7% and 80.2%). Significantly more adolescents with major depressive disorder than with other psychiatric diagnoses, especially conduct disord… Show more

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Cited by 22 publications
(2 citation statements)
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“…The dexamethasone suppression test (DST) was originally applied in the late 1960s as a laboratory diagnostic tool for major depression in adults (Carroll 1982; Carroll et al 1981). In the decades since, the DST has become the most extensively studied biological parameter of depression in adult (Casat et al 1989), as well as in child and adolescent samples (Kaufman et al 2001; Weller and Weller 1988).…”
Section: The Dexamethasone Suppression Testmentioning
confidence: 99%
“…The dexamethasone suppression test (DST) was originally applied in the late 1960s as a laboratory diagnostic tool for major depression in adults (Carroll 1982; Carroll et al 1981). In the decades since, the DST has become the most extensively studied biological parameter of depression in adult (Casat et al 1989), as well as in child and adolescent samples (Kaufman et al 2001; Weller and Weller 1988).…”
Section: The Dexamethasone Suppression Testmentioning
confidence: 99%
“…Studies on DST responses in the youth population have yielded variable results, probably due to a large number of small-sampled studies and ununified dexamethasone doses [ 32 ]. The first systematic review of the studies on the DST in depressed youth dates back to 1989 and was performed by Casat et al [ 33 ]. Their review involved 13 studies and included 145 children and 475 adolescents.…”
Section: Introductionmentioning
confidence: 99%