The Dynamics of Antimicrobial-Resistant Campylobacter jejuni on Japanese Broiler Farms

Ishihara, Katsuya; Yano, Sayoko; Nishimura, Maki; Asai, Tetsuo; Kojima, Akira; Takahashi, Toshio; Tsutsumi, Yutaka

doi:10.1292/jvms.68.515

Cited by 11 publications

(6 citation statements)

References 27 publications

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“…clones to continue to persist on broiler farms as a consequence of infection carry-over between chicken flocks. This hypothesis is supported by a previous study, in which specific C. jejuni clones were detected in chicken flocks at different time periods on broiler farms [10]. It is also possible that colonized broiler flocks contaminate the environment around broiler farms.…”

supporting

confidence: 79%

Effects of climatic elements on Campylobacter-contaminated chicken products in Japan

et al. 2011

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Japanese weather data for areas that produced Campylobacter spp.-positive chicken products were compared with those for areas producing negative samples. Regarding samples produced during the period of rising temperature (spring and summer), the mean weekly air temperatures for Campylobacter-positive samples were higher than those for negative samples for the period of the week in which the samples were purchased (18.7 °C vs. 13.1 °C, P = 0.006) to a 12-week lag (12 weeks before purchasing samples; 7.9 °C vs. 3.4 °C, P = 0.009). Significant differences in weekly mean minimum humidity and sunshine duration per day were also observed for 1- and 2-week lag periods. We postulated that the high air temperature, high humidity and short duration of sunshine for the chicken-rearing period increased Campylobacter colonization in chickens during the period of rising temperature. Consequently, the number of Campylobacter-contaminated chicken products on the market in Japan may fluctuate because of the climatic conditions to which reared chickens are exposed.

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supporting

confidence: 79%

Effects of climatic elements on Campylobacter-contaminated chicken products in Japan

et al. 2011

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“…The administration of fluoroquinolone to livestock has been regarded as a major cause of the increase in resistant strains Gupta et al, 2004 . However, more recent studies have reported the detection of resistant strains at farms where fluoroquinolones have not been used Asai et al, 2007;Ishihara et al, 2006 . This finding indicates that the occurrence of resistant strains is not necessarily linked to the use of antibacterial agents at farms.…”

Section: Discussionmentioning

confidence: 99%

Distribution of Antimicrobial Resistance in <i>Campylobacter</i> Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan

2015

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Fifty strains of Campylobacter jejuni/coli were detected in 108 specimens of chicken meat and organs sampled at six supermarkets and one poultry slaughterhouse (large scale) between April and October 2013 (isolation rates: 84.8% from the slaughterhouse, 29.3% from the supermarkets). 46/50 strains were successfully recovered and subjected to the E-test to examine their susceptibility to three fluoroquinolone antibacterial agents authorized for use in poultry in Japan: enrofloxacin (ERFX), ofloxacin (OFLX), and norfloxacin (NLFX). 29 isolates (63%) were resistant to all three agents and 2 isolates (4.3%) were resistant to two agents (ERFX and OFLX). The resistance rates of strains isolated fom the supermarkets and slaughterhouse were 61.9% and 72.0%, respectively. Because the chickens processed at the slaughterhouse were raised without the use of fluoroquinolone, the results did not suggest a positive relationship between the use of these agents and the distribution of antimicrobial-resistant bacteria. Susceptibility to macrolide antibiotics (erythromycin [EM]) was also tested in 42 strains, and one strain (2.4%), C. coli from a retailer sample, showed resistance. Previous studies have detected high rates of fluoroquinolone-resistant strains, suggesting an expanding distribution of resistant bacteria. The detection of EM-resistant bacteria downstream in the food distribution chain (i.e., closer to consumers) is a concern for human health.

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“…National level monitoring helps to realize broad prevalence of antimicrobial resistance: however, it is unable to fully figure out variability of antimicrobial resistance prevalence among farms or among herds and individuals on a farm. Detection of antimicrobial-resistant bacteria on farms usually means that the bacteria have developed antimicrobial resistance by genetic mutations or acquisition of resistance genes [41], and other resistant clones have intruded into the farms [73]. In either case, the use of antimicrobials frequently acts as selective force.…”

Section: Future Issuementioning

confidence: 99%

Role of Antimicrobial Selective Pressure and Secondary Factors on Antimicrobial Resistance Prevalence inEscherichia colifrom Food-Producing Animals in Japan

Harada

Asai

2010

Journal of Biomedicine and Biotechnology

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130

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The use of antimicrobial agents in the veterinary field affects the emergence, prevalence, and dissemination of antimicrobial resistance in bacteria isolated from food-producing animals. To control the emergence, prevalence, and dissemination of antimicrobial resistance, it is necessary to implement appropriate actions based on scientific evidence. In Japan, the Japanese Veterinary Antimicrobial Resistance Monitoring System (JVARM) was established in 1999 to monitor the antimicrobial susceptibility of foodborne and commensal bacteria from food-producing animals. The JVARM showed that the emergence and prevalence of resistant Escherichia coli were likely linked to the therapeutic antimicrobial use in food-producing animals through not only direct selection of the corresponding resistance but also indirect selections via cross-resistance and coresistance. In addition, relevant factors such as host animals and bacterial properties might affect the occurrence and prevalence of antimicrobial-resistant E. coli under the selective pressure from antimicrobial usage. This paper reviews the trends in antimicrobial resistance in E. coli and consumption of antimicrobials agents in Japan and introduces the relationship between antimicrobial usage and prevalence of antimicrobial-resistant bacteria, from food-producing animals under the JVARM program. In this paper, we will provide the underlying information about the significant factors that can help control antimicrobial resistance in bacteria in veterinary medicine.

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The Dynamics of Antimicrobial-Resistant Campylobacter jejuni on Japanese Broiler Farms

Cited by 11 publications

References 27 publications

Effects of climatic elements on Campylobacter-contaminated chicken products in Japan

Effects of climatic elements on Campylobacter-contaminated chicken products in Japan

Distribution of Antimicrobial Resistance in <i>Campylobacter</i> Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan

Role of Antimicrobial Selective Pressure and Secondary Factors on Antimicrobial Resistance Prevalence inEscherichia colifrom Food-Producing Animals in Japan

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