The Effect of a Biphasic Calcium Phosphate on Bone Healing: A Pilot Study in Rats

Abstract

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Bone Regeneration Effect of Hyperbaric Oxygen Therapy Duration on Calvarial Defects in Irradiated Rats

“…BCP is an osteoconductive material that only fills defect volume and does not induce substantial new bone formation. Previous reports showed no significant difference in the amount of new bone when using synthetic bone grafts [24, 25]. However, in this study, significant differences were found in most analyses.…”

Treatment of Non‐Contained Infrabony Defects With Enamel Matrix Derivative Alone or in Combination With Biphasic Calcium Phosphate Bone Graft: A 12‐Month Randomized Controlled Clinical Trial

“…It has been evidenced that BC is not a good osteoconductor and has a very low resorption rate 39 . Furthermore, only a very low proportion of graft particles are completely surrounded by new bone after regeneration therapy and are directly involved in bone formation 39 . The results of this investigation point to an inhibitory effect of regeneration due to the resorption process of BC, the graft surface, and morphology of graft particles.…”

“…In addition, BC has been described as an osteoconductive material 21 . However, not all the published investigations are in agreement 39 . It has been evidenced that BC is not a good osteoconductor and has a very low resorption rate 39 .…”

“…However, not all the published investigations are in agreement 39 . It has been evidenced that BC is not a good osteoconductor and has a very low resorption rate 39 . Furthermore, only a very low proportion of graft particles are completely surrounded by new bone after regeneration therapy and are directly involved in bone formation 39 .…”

Effect of BMP2–Platelet-rich Plasma–Biphasic Calcium Phosphate Scaffold on Accelerated Osteogenesis in Mastoid Obliteration

“…BCP has shown excellent biocompatibility; however, it cannot induce differentiation of mesenchymal stem cells into osteoblasts, which is required for mineralization and regeneration of bone tissue (9). For better osteogenesis of alloplastic bony scaffolds, then need for additional growth factors is gaining increasing attention.…”