The effect of an intramedullary implant with a static magnetic field on the healing of the osteotomised rabbit femur

Abstract

Static magnetic fields are a type of electromagnetic fields used in clinical practice. To ascertain what effect a static magnetic intramedullary device implanted in the rabbit femur had on fracture healing, 20 male New Zealand white rabbits with magnetic/nonmagnetic intramedullary implants were examined histologically, radiologically and for bone mineral density. Three groups were constituted according to the poles of the magnets. During surgery the intramedullary device was driven into the medulla. A femoral osteotomy was created with a mini Gigli wire at the centre point of the rod. Radiographs were obtained at the second and fourth weeks. Histological examination and bone mineral density were evaluated at the fourth week. The results of this study verified that an intramedullary implant with a static magnetic field improves bone healing in the first two weeks radiologically and that the configuration difference in magnetic poles has an effect on bone quality. Static magnetic fields have minor effects on bone mineral density values.

A Preliminary Study of the Effect of Static Magnetic Field Acting on Rat Bone Marrow Mesenchymal Stem Cells during Osteogenic Differentiation In Vitro

“…Finally, because SMF is a single physical factor, it can result less side effects comparing with varieties of physical factors such as PEMF. Since SMF has been shown to be effective in facilitating ununited fracture repair 16) and preventing bone loss 17) , it has received considerable attention about the biological effect of SMF on bone cells. A certain intensity SMF has been reported that it can significantly enhance osteoblast differentiation in vitro [18][19][20] .…”

Are there any adverse effects of static magnetic field from magnetic resonance imaging devices on bone health of workers?

“…Bu çalışmaya göre, SMA overektomize sıçanların osteoporotik omurgalarının KMY değerlerini artırmıştır. Aydın ve Bezer [13] SMA içeren intramedüller çivi-nin osteotomize sıçan femurunun iyileşmesi üzerine etkilerini araştırmışlardır. Bu araştırma sonucunda, SMA'nın erken kırık iyileşmesinde osteogenezisi baş-lattığı sonucuna varmışlardır.…”

Effect of Static Magnetic Fields on the Osseointegration of Immediately Placed Implants

“…It has been shown that SMF affects osteoblastic maturation and differentiation by upregulating local factors and inducing membrane reorientation and distortion. 20 In addition, there is evidence that SMF caused higher cell attachment and proliferation on the machined titanium surface. 27 Furthermore, effects of electromagnetic fields on cell mitotic activity, 21 changes in cell signaling pathways, 27 upregulating synthesis of transforming growth factor-b1, and increase in extracellular matrix proteins could be considered as other factors underlying the action mechanism of SMF on bone healing.…”

“…Several studies have reported that magnetic fields could enhance bone formation. 20,24,28,29 Shigino et al 24 showed that electromagnetic fields stimulate bone healing around endosseous implants in the dog mandible. Matsumoto et al 29 reported an enhanced bone formation around dental implants using PEMF.…”

“…The advantage of permanent magnets is that they do not require an external power supply to generate magnetic field. 20 There is scientific evidence that electromagnetic fields could promote bone healing. 21-24 Basset 25 demonstrated the therapeutic effects of SMFs on bone fracture repair.…”