The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized controlled clinical trial

Gheflati, Alireza; Bashiri, Reihane; Ghadiri‐Anari, Akram; Reza, Javad Zavar; Kord, Marjan Tajik; Nadjarzadeh, Azadeh

doi:10.1016/j.clnesp.2019.06.006

Cited by 40 publications

(33 citation statements)

References 52 publications

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“…e administration of apple vinegar alone or combined with Rosa canina extract resulted in different actions that lead to normalizing organs histology. Beneficial properties of vinegar and Rosa canina in the liver and kidney are documented in the literature by controlling organs damage and decreasing hepatic enzymes levels [18,[48][49][50][51][52][53].…”

Section: Discussionmentioning

confidence: 99%

Effect of a Combination of Rosa canina Fruits and Apple Cider Vinegar against Hydrogen Peroxide-Induced Toxicity in Experimental Animal Models

Ousaaid

Laaroussi

Bakour

et al. 2022

Journal of Food Quality

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Oxidative stress is the trigger of several diseases. It is an imbalance between the production of free radicals and antioxidants. This study aims to evaluate the antioxidant capacity and the protective property of Rosa canina fruits and apple cider vinegar combined or not against hydrogen peroxide (H2O2)-induced toxicity in Wistar rats. The experiment included five groups: group 1 received distilled water (10 mL/kg b.wt), group 2 received H2O2 10% (10 mL/kg b.wt), group 3 received H2O2 10% (10 mL/kg b.wt) and apple vinegar (2 mL/kg b.wt); group 4 received H2O2 10% (10 mL/kg b.wt) and apple vinegar supplemented with Rosa canina fruits extract (300 mg/kg b.wt); group 5 received H2O2 10% (10 mL/kg b.wt) and extract of Rosa canina fruits (300 mg/kg b.wt). The doses were given once daily via a gavage. The antioxidant capacity of apple vinegar and Rosa canina extract was analyzed, and AST, ALT, PAL, urea, and creatinine were determined on day 22 of the experiment. In addition, the kidney and the liver tissues were analyzed. The results showed that H2O2 caused a significant elevation of blood urea, blood creatinine, and transaminases. The histopathology examination revealed that H2O2 caused congestion, hemorrhage, and Bowman’s space enlarged. On the other hand, the results clearly showed that apple vinegar and Rosa canina fruits counterbalance the biochemical and histological changes induced by H2O2. In conclusion, the two natural products studied in this work are effective against the harmful effect of oxidative stress, which explains their use in traditional medicine.

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Section: Discussionmentioning

confidence: 99%

Effect of a Combination of Rosa canina Fruits and Apple Cider Vinegar against Hydrogen Peroxide-Induced Toxicity in Experimental Animal Models

Ousaaid

Laaroussi

Bakour

et al. 2022

Journal of Food Quality

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“…The current interest focuses on determination of the antiproliferative effects of these natural products on cancer cells (Gill et al, 2005;Tavakoli et al, 2012;Huang et al, 2019;Tutun et al, 2020). Vinegar, which is a plant-based product, has been widely consumed for treating several human disorders such as hyperglycemia, hyperlipidemia, cancer and oxidative stress due to their bioactive substances and various beneficial effects on health (Gheflati et al, 2019;Mohamad et al, 2019;Ousaaid et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Investigation of Antiproliferative Effects of Home-Made and Commercial Apple Vinegars on Myeloma Cells

Kaya

Tutun

Usluer

et al. 2021

Turkish JAF Sci.Tech.

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Vinegar is an aqueous food product made by a succession of yeast and acetic acid bacteria activities from fruits that contain high carbohydrates such as apples and grapes. Vinegar has been used as a dietary spice and natural remedy since ancient times due to its therapeutic properties including antimicrobial, antidiabetic, and anticancer activities. It has been shown that some bioactive compounds exhibiting antioxidant activity in vinegars lead to anticancer activity. The aim of the present study was to investigate antiproliferative effect of commercial and home-made apple vinegars in native and neutralized form on myeloma cells. In order to neutralize the vinegars, sodium hydroxide (NaOH) was used. A serial two-fold dilutions of the vinegars (50%, 25%, 12.5%, 6.25%, 3.12%, 1.56%, 0.78%, 0.39%) prepared with cell medium were treated to the cells. The MTT (3-(4.5-Dimethylthiazol-2-yl)-2.5-Diphenyltetrazolium Bromide) assay was used to determine the cellular viability in the cells treated with the vinegars. In this study, while commercial vinegar possessed a stronger antiproliferative activity than home-made vinegar, all native vinegars possessed stronger antiproliferative effect than neutralized vinegars. Interestingly, when home-made vinegar (both native and neutralized) concentrations were from 6.25 to 1.56%, the cell viability increased. Apple vinegar exhibited antiproliferative activity on myeloma cells; however, further studies are required to clarify the mechanisms underlying this activity.

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“…Obecny stan wiedzy wskazuje, że ocet wykazuje m.in. właściwości obniżające ciśnienie krwi [16] oraz stężenie cholesterolu [17] i przeciwdziałające efektom cukrzycy [18]. Może również zapobiegać rozwojowi chorób sercowo-naczyniowych [19], stłuszczeniu wątroby [20] oraz otyłości [21].…”

Section: Wprowadzenie I Cel Pracyunclassified

Grape vinegars – characteristics, properties and safety of use

Antoniewicz¹,

Janda-Milczarek²

2021

Med Og Nauk Zdr.

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Wprowadzenie i cel pracy. Ocet jest fermentowanym produktem rozpowszechnionym na całym świecie. Stosowany jest przede wszystkim jako przyprawa w celu wzbogacenia smaku dań oraz utrwalenia żywności w postaci marynat. Ocet może jednak stanowić źródło wielu związków o pozytywnym wpływie na organizm człowieka. Celem pracy jest przybliżenie tematyki związanej z różnego rodzaju octami wytworzonymi z owoców winogron oraz ich właściwości zdrowotnych. Metody przeglądu. Systematycznego przeglądu badań dokonano na podstawie przeszukiwania elektronicznych baz danych takich jak PubMed, Elsevier oraz Google Scholar. Opis stanu wiedzy. Octy owocowe, w tym octy winogronowe, stanowią bogate źródło witamin, związków mineralnych, kwasów organicznych oraz związków polifenolowych, dzięki którym wykazują pozytywne działanie na organizm człowieka. Z racji zawartości związków o działaniu antyoksydacyjnym produkt ten może być stosowany wspomagająco w terapii schorzeń o podłożu wolnorodnikowym, np. chorób układu sercowo-naczyniowego. Skład i jakość produktu finalnego warunkowane są doborem surowca wyjściowego, metodą produkcji, jak i mikroorganizmami biorącymi udział w procesie fermentacji. Octy winogronowe wykazują korzystny wpływ na gospodarkę węglowodanową, obniżając stężenie glukozy na czczo, hemoglobiny A1c, ale również glikemii poposiłkowej. Badania wskazują, że octy winogronowe wpływają również pozytywnie na profil lipidowy, obniżając stężenie cholesterolu całkowitego oraz jego frakcji LDL. Podsumowanie. Octy winogronowe są bogatym źródłem wielu związków bioaktywnych, dzięki czemu mogą być stosowane we wspomaganiu terapii niektórych schorzeń, głównie o podłożu wolnorodnikowym. Zawartość poszczególnych związków w octach winogronowych jest silnie zróżnicowana, a na ich kompozycję wpływa zarówno proces produkcji octu, jak i wykorzystana odmiana winogron.

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The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized controlled clinical trial

Cited by 40 publications

References 52 publications

Effect of a Combination of Rosa canina Fruits and Apple Cider Vinegar against Hydrogen Peroxide-Induced Toxicity in Experimental Animal Models

Effect of a Combination of Rosa canina Fruits and Apple Cider Vinegar against Hydrogen Peroxide-Induced Toxicity in Experimental Animal Models

Investigation of Antiproliferative Effects of Home-Made and Commercial Apple Vinegars on Myeloma Cells

Grape vinegars – characteristics, properties and safety of use

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