The effect of material composition of 3-dimensional graphene oxide and self-doped polyaniline nanocomposites on DNA analytical sensitivity

Yang, Tao; Chen, Huaiyin; Yang, Ruirui; Wang, Xinxing; Nan, Fuxin; Jiao, Kui

doi:10.1016/j.colsurfb.2015.05.035

Cited by 7 publications

(3 citation statements)

References 36 publications

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“…Generally, 3D graphene can be achieved as 3D reduced graphene oxide (3D-rGO) from reducing 3D graphene oxide (3D-GO) or chemically integrating from 2D-rGO sheets via gelation technologies [37]. 3D-rGO shows superior bioelectrochemical performance due to its high specific surface area, unique morphology and structure, a large number of electroactive sites and acceleration of electron transfer [38,39].…”

Section: Introductionmentioning

confidence: 99%

Employing Label‐free Electrochemical Biosensor Based on 3D‐Reduced Graphene Oxide and Polyaniline Nanofibers for Ultrasensitive Detection of Breast Cancer BRCA1 Biomarker

Xia

Chen

et al. 2020

Electroanalysis

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A label‐free DNA biosensor based on three‐dimensional reduced graphene oxide (3D‐rGO) and polyaniline (PANI) nanofibers modified glassy carbon electrode (GCE) was successfully developed for supersensitive detection of breast cancer BRCA1. The results demonstrated that 3D‐rGO and PANI nanofibers had synergic effects for reducing the charge transfer resistance (Rct), meaning a huge enhancement in electrochemical activity of 3D‐rGO‐PANI/GCE. Probe DNA could be immobilized on 3D‐rGO‐PANI/GCE for special and sensitive recognition of target DNA (1.0×10−15–1.0×10−7 M) with a theoretical LOD of 3.01×10−16 M (3S/m). Furthermore, this proposed nano‐biosensor could directly detect BRCA1 in real blood samples.

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Section: Introductionmentioning

confidence: 99%

Employing Label‐free Electrochemical Biosensor Based on 3D‐Reduced Graphene Oxide and Polyaniline Nanofibers for Ultrasensitive Detection of Breast Cancer BRCA1 Biomarker

Xia

Chen

et al. 2020

Electroanalysis

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“…To prevent more women from cancers arising from BRCA1 gene mutation, detection of BRCA1 gene mutation is of crucial importance as it usually facilitates diagnosis and intervention [29,30]. Recently, 3D-rGO has been reported to display excellent bioelectrochemical performance owing to its enhanced surface area, special morphology and structure, a lot of electroactive sites as well as the expedition of electron transfer [31,32]. PANI nanofibers, on the other hand, are an effective conductive electroactive polymer with large surface area, mechanical flexibility, adjustable conductivity, chemical uniqueness as well as simple processing, hence the suitability as a potential material in the development of extremely sensitive biosensors [33][34][35][36].…”

Section: Graphene and Its Derivativesmentioning

confidence: 99%

Using Nanomaterials as Excellent Immobilisation Layer for Biosensor Design

et al. 2023

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“…SPAns have been applied in diverse applications such as solar cells , fuel cells , batteries , electrochromic devices , electrocatalysis , corrosion protection , supercapacitors and sensors . The deposition of copper species on SPAn films has been explored and used for the fabrication of chemical sensors; an electrochemical sensor for the determination of hydrogen peroxide was constructed by electrodeposition of Cu nanoparticles on the precursor film poly‐p‐aminobenzene sulfonic acid electrodeposited on glassy carbon (GC) electrode .…”

Section: Introductionmentioning

confidence: 99%

Electrochemically Generated Recognition Sites in Self‐doped Polyaniline Modified Electrodes for Voltammetric and Potentiometric Determination of Copper(II) Ion

Mohammadabadi

Zanganeh

2017

Electroanalysis

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Chemical recognition elements for copper(II) ion have been generated in electrodes modified with poly(aniline‐co‐metanilic acid), P(An‐co‐MA), membrane and the resulting electrodes were used as selective sensors for voltammetric and potentiometric determination of this ion in an extended pH range. The P(An‐co‐MA) membrane was electrodeposited from aqueous mixed monomer solutions of An and MA, without the presence of a supporting electrolyte. For generating the recognition elements, P(An‐co‐MA) modified electrodes were subjected to several consecutive reduction/oxidation potential steps in copper(II) ion solution. It seems that during these potential steps, the receptor sites of the membrane are adjusted to the size, complexing property and hard/soft nature of copper(II) ion. This electrochemically mediated templating process, provided a selective sensor for determination of copper(II) ion. The results of preconcentration/differential pulse anodic stripping voltammetry, indicated analytical relation between the peak current and concentration of copper(II) from 1.0×10−9 to 1.0×10−4 M. The interference effect of various metal ions was explored and it was found that only mercury and silver ions show a considerable interference. The sensor exhibited selective potentiometric response for copper(II) over a wide concentration range (1.0×10−8 to 1.0×10−3 M) with a Nernstian slope of 27.9±0.3 mV per decade of copper(II) ion activity.

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The effect of material composition of 3-dimensional graphene oxide and self-doped polyaniline nanocomposites on DNA analytical sensitivity

Cited by 7 publications

References 36 publications

Employing Label‐free Electrochemical Biosensor Based on 3D‐Reduced Graphene Oxide and Polyaniline Nanofibers for Ultrasensitive Detection of Breast Cancer BRCA1 Biomarker

Employing Label‐free Electrochemical Biosensor Based on 3D‐Reduced Graphene Oxide and Polyaniline Nanofibers for Ultrasensitive Detection of Breast Cancer BRCA1 Biomarker

Using Nanomaterials as Excellent Immobilisation Layer for Biosensor Design

Electrochemically Generated Recognition Sites in Self‐doped Polyaniline Modified Electrodes for Voltammetric and Potentiometric Determination of Copper(II) Ion

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