The effect of tandem-ovoid titanium applicator on points A, B, bladder, and rectum doses in gynecological brachytherapy using  192 Ir

Sadeghi, M. H.; Sina, Sedigheh; Mehdizadeh, Amir; Faghihi, Reza; Moharramzadeh, Vahed; Meigooni, Ali S.

doi:10.5114/jcb.2018.74314

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…Then, the plans were checked by calculating an equivalent dose in 2 Gy fractions (EQD 2 ) to D 90 of > 85 Gy (assuming that the patient was being treated with a given applicator in five fractions). For organs at risk, the doses recommended by the GEC-ESTRO were as follows: rectum, D 2cc < 75 Gy; sigmoid, D 2cc < 75 Gy; and bladder, D 2cc < 90 Gy [8,9]. When the recommended doses could not be achieved, the D 90 was lowered to 80 Gy in the early stage small HR-CTV volume patients and in two patients, the use of a second type of applicator achieved a better HR-CTV.…”

Section: Methodsmentioning

confidence: 99%

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A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer

Gürsel¹,

Serarslan²,

Meydan³

et al. 2020

jcb

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Purpose: The standard treatment for locally advanced stage cervical cancer is definitive radiotherapy, the quality of which affects both survival and side effects. Brachytherapy is a major component of definitive radiotherapy; it is administered using different techniques and applicators. The purpose of this study was to dosimetrically compare tandem ovoid (T-ovoid) and tandem ring (T-ring) brachytherapy treatments. Material and methods: Both applicator sets were applied to the same 20 patients, and treatment plans were made three-dimensionally (3D), with high-risk clinical target volume (HR-CTV) and organs at risk contoured. The HR-CTV was defined according to post-external magnetic resonance results. The patients with residual tumors not exceeding one-third of the parametrium were included in this study, while patients with larger masses were excluded and received interstitial therapy. The doses were calculated for both plans. Optimization for the HR-CTV was made with the aim that the equivalent dose according to 2 Gy (EQD 2) of 90% of the HR-CTV (D 90) would be higher than 85 Gy, without exceeding the maximum dose for organs at risk. Then, pairwise dosimetric comparisons were performed. Results: Plans were compared dosimetrically according to the HR-CTV, point A and B doses, and organs at risk. Although the point A and B doses were higher with T-ovoid use, the 3D HR-CTV coverage was statistically better with T-ring application (EQD 2 of HR-CTV D 90 : 97.46 Gy for T-ring and 88.44 Gy for T-ovoid; p < 0.0001). In addition, the rectum and bladder doses were statistically lower with T-ring usage (EQD 2 of rectum, 2 cc; T-ring, 63.10 Gy; T-ovoid, 74.99 Gy; p < 0.0001; EQD 2 of bladder, 2 cc; T-ring, 85.26 Gy; T-ovoid, 89.05 Gy; p < 0.0001). Conclusions: In our study with a limited number of samples, T-ring applicator seems to offer better 3D brachytherapy dosimetry for both HR-CTV and nearby organs at risk.

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Section: Methodsmentioning

confidence: 99%

“…The quality of definitive radiotherapy both increases loco-regional control rates and decreases side effects [5,6,7]. Although the Manchester system has been widely used with these treatments, the target area coverage and radiation risk to nearby tissues are still uncertain [8].…”

Section: Purposementioning

confidence: 99%

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer

Gürsel¹,

Serarslan²,

Meydan³

et al. 2020

jcb

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Assessing Heterogeneity Effects on Points A, B, and Organs at Risk Doses in High-dose-Rate Brachytherapy for Cervical Cancer – A Comparison of 192Ir and 60Co Sources Using Monte Carlo N-Particle 5

Sadeghi,

Sina,

Meigooni

2024

Journal of Medical Physics

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Purpose: The present article deals with investigating the effects of tissue heterogeneity consideration on the dose distribution of 192Ir and 60Co sources in high-dose-rate brachytherapy (HDR-BT). Materials and Methods: A Monte Carlo N-Particle 5 (MCNP5) code was developed for the simulation of the dose distribution in homogeneous and heterogeneous phantoms for cervical cancer patients. The phantoms represented water-equivalent and human body-equivalent tissues. Treatment data for a patient undergoing HDR-BT with a 192Ir source were used as a reference for validation, and for 60Co, AAPM Task Group 43 methodology was also applied. The dose values were calculated for both source types in the phantoms. Results: The results showed a good agreement between the calculated dose in the homogeneous phantom and the real patient’s treatment data, with a relative difference of less than 5% for both sources. However, when comparing the absorbed doses at critical points such as Point A right, Point A left, Point B right, Point B left, bladder International Commission on Radiation Units and Measurement (ICRU) point, and recto-vaginal ICRU point, the study revealed significant percentage differences (approximately 5.85% to 12.02%) between the homogeneous and heterogeneous setups for both 192Ir and 60Co sources. The analysis of dose–volume histograms (DVH) indicated that organs at risk, notably the rectum and bladder, still received doses within recommended limits. Conclusions: The study concludes that 60Co and 192Ir sources can be effectively used in HDR-BT, provided that careful consideration is given to tissue heterogeneity effects during treatment planning to ensure optimal therapeutic outcomes.

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Verification of Dose Distribution in Cervical Cancer Brachytherapy Using Metal and Plastic Applicators

Tomita

Fuse

Fujisaki

et al. 2023

Nippon Hoshasen Gijutsu Gakkai Zasshi

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Purpose: To validate the point-A dose and dose distribution of metal and resin applicators in comparison with those of TG-43U1. Methods: The metal and resin applicators consisting of tandem and ovoid were modeled by the egs_brachy. The doses to point A and dose distributions considering each applicator were calculated and compared to those of TG-43U1. Results: The dose to point A considering the metal applicator was 3.2% lower than that of TG-43U1, but there was no difference in the dose to point A considering the resin applicator. The dose distribution considering the metal applicator was lower than that of TG-43U1 at all calculation points, but there was no difference in the dose distribution considering the resin applicator at almost all calculation points. Conclusion: In this study, the dose distribution considering the metal applicator was lower than that of TG-43U1 at all calculation points, but there was no difference in the dose distribution considering the resin applicator at almost all calculation points. Therefore, TG-43U1 can accurately calculate the dose distribution when changing from the metal applicator to the resin applicator.

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The effect of tandem-ovoid titanium applicator on points A, B, bladder, and rectum doses in gynecological brachytherapy using 192 Ir

Cited by 3 publications

References 19 publications

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer

A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer

Assessing Heterogeneity Effects on Points A, B, and Organs at Risk Doses in High-dose-Rate Brachytherapy for Cervical Cancer – A Comparison of 192Ir and 60Co Sources Using Monte Carlo N-Particle 5

Verification of Dose Distribution in Cervical Cancer Brachytherapy Using Metal and Plastic Applicators

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