The effect of the nasal cycle on mucociliary clearance

Soane, R. J.; Carney, A. Simon; Jones, Nick; Frier, M.; Ac, Perkins; Davis, S. S.; Illum, Lisbeth

doi:10.1046/j.1365-2273.1999.00254-1.x

Cited by 13 publications

(15 citation statements)

References 17 publications

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“…In humans, nasal MCC has been investigated (92)(93)(94). These studies showed that nasal MCC was not affected by dry breathing air in young healthy persons (92) but mucociliary speed decreased progressively in 174 test persons (different ages and genders) when RH of breathing air was reduced from 70% to 20% (93).…”

Section: Mucociliary Clearancementioning

confidence: 99%

Seasonality of Respiratory Viral Infections

2020

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The seasonal cycle of respiratory viral diseases has been widely recognized for thousands of years, as annual epidemics of the common cold and influenza disease hit the human population like clockwork in the winter season in temperate regions. Moreover, epidemics caused by viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and the newly emerging SARS-CoV-2 occur during the winter months. The mechanisms underlying the seasonal nature of respiratory viral infections have been examined and debated for many years. The two major contributing factors are the changes in environmental parameters and human behavior. Studies have revealed the effect of temperature and humidity on respiratory virus stability and transmission rates. More recent research highlights the importance of the environmental factors, especially temperature and humidity, in modulating host intrinsic, innate, and adaptive immune responses to viral infections in the respiratory tract. Here we review evidence of how outdoor and indoor climates are linked to the seasonality of viral respiratory infections. We further discuss determinants of host response in the seasonality of respiratory viruses by highlighting recent studies in the field. 2.1

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Section: Mucociliary Clearancementioning

confidence: 99%

Seasonality of Respiratory Viral Infections

2020

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“…In der Ruhephase liegt dagegen ein erh ö hter Widerstand mit verringertem hydraulischen Durchmesser, geringerem transnasalen Flow und verringerter Turbulenz vor [53] . Die mukozili ä re Clearance ist w ä hrend der Arbeitsphase 2,5 mal h ö her als in der kontralateralen Ruhephase [58] . Die Ruhephase dient zur Feuchtigkeitssammlung [59,60] .…”

Section: Nasenzyklusunclassified

Funktionen und Funktionsstörungen der respiratorischen Schleimhaut der Nase und der Nasennebenhöhlen

Beule¹

2010

Laryngo-Rhino-Otol

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In this review, anatomy and physiology of the respiratory mucosa of nose and paranasal sinuses are summarized under the aspect of its clinical significance. Basics of endonasal cleaning including mucociliary clearance and nasal reflexes, as well as defence mechanisms are explained. Physiological wound healing, aspects of endonasal topical medical therapy and typical diagnostic procedures to evaluate the respiratory functions are presented. Finally, the pathophysiologies of different subtypes of non-allergic rhinitis are outlined together with treatment recommendations.

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“…In addition, unlike rhinoscintigraphy, the STT could not supply objective and detailed information for quantitative analyses [12]. Furthermore, rhinoscintigraphy provides more accurate test results than the STT [31,32]. Although rhinoscintigraphy is a reliable and easily reproducible method, low-dose radiation exposure is a disadvantage of the technique [33].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of nasal mucociliary activity in patients with chronic renal failure

Kucur

Özbay

Gülcan

et al. 2015

Eur Arch Otorhinolaryngol

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The ability of respiratory mucosal surfaces to eliminate foreign particles and pathogens and to keep mucosal surfaces moist and fresh depends on mucociliary activity. Chronic renal failure (CRF) is an irreversible medical condition that may result in important extrarenal systemic consequences, such as cardiovascular, metabolic, and respiratory system abnormalities. Although there are studies describing nasal manifestations of CRF, data are lacking concerning the effects of the condition on nasal mucosa. The goal of the current study was to evaluate nasal mucociliary clearance (NMC) time in patients with CRF. This prospective cohort study conducted in a tertiary referral center included 32 non-diabetic end-stage CRF patients and 30 control individuals. The control group consisted of voluntary participants who had been referred to our clinic for symptoms other than rhinological diseases. The mean NMC times in CRF patients and control individuals were 12.51 ± 3.74 min (range 7-22 min) and 8.97 ± 1.83 min (range 6-13 min), respectively. The mean NMC time in patients with CRF was significantly longer than that in control individuals (p < 0.001). Clinicians must keep in mind that NMC time in CRF patients is prolonged and must follow-up these patients more closely for sinonasal and middle ear infections.

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The effect of the nasal cycle on mucociliary clearance

Cited by 13 publications

References 17 publications

Seasonality of Respiratory Viral Infections

Seasonality of Respiratory Viral Infections

Funktionen und Funktionsstörungen der respiratorischen Schleimhaut der Nase und der Nasennebenhöhlen

Evaluation of nasal mucociliary activity in patients with chronic renal failure

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