The effects of a low-carbohydrate diet on oxygen saturation in heart failure patients: a randomized controlled clinical trial

González-Islas, Dulce; Orea-Tejeda, Arturo; Castillo-Martı́nez, Lilia; Olvera-Mayorga, Gabriela; Rodríguez-García, Wendy Daniella; Santillán-Díaz, Cira; Keirnes-Davis, Candace; Vaquero-Barbosa, Nayeli

doi:10.20960/nh.784

Cited by 9 publications

(3 citation statements)

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“…In 88 participants (53% of whom had diabetes) randomised to either a high carbohydrate diet (50% energy from carbohydrate) or a reduced carbohydrate diet (40% carbohydrate), a significant improvement in oxygen saturation was found following two months of the low‐carbohydrate diet. Changes in all other parameters did not reach statistical significance between groups, including weight and blood pressure; however, it should be noted that there was a marked reduction in weight in the low‐carbohydrate group, although failing to reach statistical significance . Similar results have also been reported previously, showing significant weight loss, improved oxygen saturation and functional class with a diet providing 40% energy from carbohydrate .…”

Section: Nutritional Recommendations For People Living With Both Diabsupporting

confidence: 79%

Dietary approaches for patients with heart failure and diabetes

2018

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Nutritional management has a key role to play in the management of diabetes and heart failure (HF). There is currently little evidence to make dietary recommendations specifically for people living with both diabetes and HF. Therefore, most nutritional management recommendations for HF and diabetes need to be based on those for people living with diabetes. This review paper details what is known about the nutritional management recommendations for people living with both diabetes and HF. The only specific approach focusing on managing HF which is currently part of nutritional recommendations are those focused upon fluid and sodium intake to reduce blood volume. There is an emerging body of evidence to suggest individuals living with both diabetes and HF could benefit from dietary pattern approaches, e.g. the Mediterranean diet. A range of dietary approaches have been shown to be effective; the key is for nutritional and dietary advice to be carefully tailored to the individual's social situation and food preferences as well as being supportive of the overall medical management of their condition. Copyright © 2018 John Wiley & Sons.

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Section: Nutritional Recommendations For People Living With Both Diabsupporting

confidence: 79%

Dietary approaches for patients with heart failure and diabetes

2018

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“…The authors observed a statistically significant improvement in oxygen saturation (SaO 2 ). These changes to SaO 2 were only observed in the LC group ( 97 ).…”

Section: Improving Body Compositionmentioning

confidence: 86%

“…Whilst an increased BMI may be beneficial for HF patients, weight reduction is known to improve overall metabolic health and increase cardiorespiratory fitness, leading to substantial improvements in disease outcomes ( 2 ). González Islas et al ( 97 ) randomized 88 stable HF patients to either a LC diet or a low fat diet as recommended by the American Heart Association. The authors observed a statistically significant improvement in oxygen saturation (SaO 2 ).…”

Section: Improving Body Compositionmentioning

confidence: 99%

Low Carbohydrate Diets for Diabetic Cardiomyopathy: A Hypothesis

et al. 2022

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Elevated blood glucose levels, insulin resistance (IR), hyperinsulinemia and dyslipidemia the key aspects of type 2 diabetes mellitus (T2DM), contribute to the development of a certain form of cardiomyopathy. This cardiomyopathy, also known as diabetic cardiomyopathy (DMCM), typically occurs in the absence of overt coronary artery disease (CAD), hypertension or valvular disease. DMCM encompasses a variety of pathophysiological processes impacting the myocardium, hence increasing the risk for heart failure (HF) and significantly worsening outcomes in this population. Low fat (LF), calorie-restricted diets have been suggested as the preferred eating pattern for patients with HF. However, LF diets are naturally higher in carbohydrates (CHO). We argue that in an insulin resistant state, such as in DMCM, LF diets may worsen glycaemic control and promote further insulin resistance (IR), contributing to a physiological and functional decline in DMCM. We postulate that CHO restriction targeting hyperinsulinemia may be able to improve tissue and systemic IR. In recent years low carbohydrate diets (LC) including ketogenic diets (KD), have emerged as a safe and effective tool for the management of various clinical conditions such as T2DM and other metabolic disorders. CHO restriction achieves sustained glycaemic control, lower insulin levels and successfully reverses IR. In addition to this, its pleiotropic effects may present a metabolic stress defense and facilitate improvement to cardiac function in patients with HF. We therefore hypothesize that patients who adopt a LC diet may require less medications and experience improvements in HF-related symptom burden.

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Nutrition in chronic heart failure patients: a systematic review

Bianchi

2019

Heart Fail Rev

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The effects of a low-carbohydrate diet on oxygen saturation in heart failure patients: a randomized controlled clinical trial

Abstract: Low-carbohydrate diet may improve the oxygen saturation in patients with chronic stable heart failure.

Cited by 9 publications

References 0 publications

Dietary approaches for patients with heart failure and diabetes

Dietary approaches for patients with heart failure and diabetes

Low Carbohydrate Diets for Diabetic Cardiomyopathy: A Hypothesis

Nutrition in chronic heart failure patients: a systematic review

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